Effect of Blood Flow on Double Inversion Recovery Vessel Wall MRI of the Peripheral Arteries: Quantitation With T2 Mapping and Comparison With Flow-Insensitive T2-Prepared Inversion Recovery Imaging
Effect of Blood Flow on Double Inversion Recovery Vessel Wall MRI of the Peripheral Arteries: Quantitation With T2 Mapping and Comparison With Flow-Insensitive T2-Prepared Inversion Recovery Imaging
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DOI：
10.1002/mrm.22227
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发表时间：
2010-03-01
影响因子：
3.3
通讯作者：
Wang, Yi
中科院分区：
文献类型：
--
作者：
Brown, Ryan;Nguyen, Thanh D.;Wang, Yi
由于血流缓慢，使用依赖于血流的方法（如双反转恢复）进行下肢血液抑制可能会出现问题。使用快速自旋回波（FSE）采集的T-2标测用于量化13名受试者中双反转恢复血液抑制的有效性，结果显示腘动脉中25 +/- 12%的感知血管壁像素包含人为血液信号。为了克服这个问题，实施了一种对流量不敏感的T-2准备的反转恢复序列，并计算了FSE采集的最佳定时参数。在相同的13名受试者中，使用二维T-2准备的反转恢复-FSE进行腘动脉和股动脉的黑色血管壁成像。与二维双反转恢复-FSE的比较表明，T-2准备的反转恢复-FSE减少了血管壁模拟血液伪影，这些伪影使腘动脉中的双反转恢复-FSE血管壁面积测量值膨胀。Magn Reson Med 63：736-744，2010. (C)2010 Wiley-Liss，Inc.
Blood suppression in the lower extremities using flow-reliant methods such as double inversion recovery may be problematic due to slow blood flow. T-2 mapping using fast spin echo (FSE) acquisition was utilized to quantitate the effectiveness of double inversion recovery blood suppression in 13 subjects and showed that 25 +/- 12% of perceived vessel wall pixels in the popliteal arteries contained artifactual blood signal. To overcome this problem, a flow-insensitive T-2-prepared inversion recovery sequence was implemented and optimal timing parameters were calculated for FSE acquisition. Black blood vessel wall imaging of the popliteal and femoral arteries was performed using two-dimensional T-2-prepared inversion recovery-FSE in the same 13 subjects. Comparison with two-dimensional double inversion recovery-FSE showed that T-2-prepared inversion recovery-FSE reduced wall-mimicking blood artifacts that inflated double inversion recovery-FSE vessel wall area measurements in the popliteal artery. Magn Reson Med 63:736-744, 2010. (C) 2010 Wiley-Liss, Inc.