Modeling the internal pressure dependence of thermal conductivity and in vitro temperature measurement for lung RFA
Modeling the internal pressure dependence of thermal conductivity and in vitro temperature measurement for lung RFA
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DOI：
10.1109/iembs.2011.6091424
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发表时间：
2011-12
期刊：
影响因子：
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通讯作者：
N. Yamazaki;Hiroki Watanabe;M. Seki;T. Hoshi;Yo Kobayashi;T. Miyashita;M. Fujie
中科院分区：
文献类型：
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作者：
N. Yamazaki;Hiroki Watanabe;M. Seki;T. Hoshi;Yo Kobayashi;T. Miyashita;M. Fujie
在过去的几年里，射频消融(RFA)在肺癌治疗中的应用越来越多，因为RFA是对患者进行的微创治疗。作为RFA治疗肺癌的一个特征，肺具有低导热系数的空气。因此，肺RFA的优点是仅对肿瘤进行凝固，因为加热区仅限于加热点附近。然而，由于成像方式的不足，操作者很难精确地控制凝固区的形成。为了克服目前的不足，我们提出了一种用数值模拟的方法来分析器官的温度分布。由于器官的热物理性质的复杂性，建立一个准确的热物理模型是一个具有挑战性的问题。在本工作中，作为消融模拟器的开发过程，测量了肺热导率的压力依赖关系，并在体外估计了射频消融过程中的温度分布。
Radio frequency ablation (RFA) for lung cancer has increasingly been used over the past few years because RFA is minimally invasive treatment for patients. As a feature of RFA for the lung cancer, lung has the air having low thermal conductivity. Therefore, RFA for lung has the advantage that only the tumor is coagulated because heating area is confined to the immediate vicinity of the heating point. However, it is difficult for operators to control the precise formation of coagulation zones due to inadequate imaging modalities. We propose a method using numerical simulation to analyze the temperature distribution of the organ in order to overcome the current deficiencies. Creating an accurate thermophysical model was a challenging problem because of the complexities of the thermophysical properties of the organ. In this work, as the processes in the development of ablation simulator, measurement of the pressure dependence of lung thermal conductivity and in vitro estimation of the temperature distribution during RFA is presented.