Rapid psychosocial function screening test identified treatment failure in HIV+ African youth.

Rapid psychosocial function screening test identified treatment failure in HIV+ African youth.
复制标题

DOI:
10.1080/09540121.2011.644233
复制
发表时间:
2012
期刊:
影响因子:
1.7
通讯作者:
Gross R
Gross R
中科院分区:
医学4区
文献类型:
--
作者:
Lowenthal E;Lawler K;Harari N;Moamogwe L;Masunge J;Masedi M;Matome B;Seloilwe E;Gross R

文献摘要

参考文献

被引文献

相似文献

年龄较大的儿童和青少年的心理社会功能障碍很常见,可能导致不坚持艾滋病毒治疗。坚持性差导致艾滋病毒治疗失败和耐药病毒的发展。在资源有限的情况下,治疗选择通常仅限于一种或两种可用的治疗线,在失败发生之前识别失败风险最高的个体至关重要。心理社会功能障碍的快速筛查工具可以帮助确定哪些儿童和青少年最有可能从旨在防止艾滋病毒治疗失败的有限心理社会支助服务中受益。儿科症状检查表(PSC)用于高资源环境中快速识别高危青少年。在博茨瓦纳的692名接受治疗的HIV感染儿童(8-<17岁)中,PSC得分高与病毒学失败相关(OR 1.7,95% CI 1.1-2.6)。PSC可能是儿科HIV的一种有用的筛查工具。
Psychosocial dysfunction in older children and adolescents is common and may lead to non-adherence to HIV treatments. Poor adherence leads to HIV treatment failure and the development of resistant virus. In resource-limited settings where treatment options are typically limited to only one or two available lines of therapy, identification of individuals at highest risk of failure before failure occurs is of critical importance. Rapid screening tools for psychosocial dysfunction may allow for identification of those children and adolescents who are most likely to benefit from limited psychosocial support services targeted at preventing HIV treatment failure. The Pediatric Symptom Checklist (PSC) is used in high resource settings for rapid identification of at-risk youth. In 692 HIV-infected treated children (ages of 8-<17 years) in Botswana, having a high score on the PSC was associated with having virologic failure (OR 1.7, 95% CI 1.1–2.6). The PSC may be a useful screening tool in pediatric HIV.
DOI: 10.1542/peds.112.1.129
发表时间: 2003-07-01
期刊: PEDIATRICS
影响因子: 8
作者:
Borowsky, IW;Mozayeny, S;Ireland, M
通讯作者: Ireland, M
DOI: 10.1097/01.inf.0000143646.15240.ac
发表时间: 2004-11-01
影响因子: 3.6
作者:
Mellins, CA;Brackis-Cott, E;Abrams, EJ
通讯作者: Abrams, EJ
DOI: 10.1016/j.pec.2009.07.014
发表时间: 2010-04
影响因子: 3.5
作者:
Murphy DA;Lam P;Naar-King S;Robert Harris D;Parsons JT;Muenz LR;Adolescent Medicine Trials Network for HIV/AIDS Interventions
通讯作者: Adolescent Medicine Trials Network for HIV/AIDS Interventions
DOI: 10.2471/blt.09.066126
发表时间: 2010-06-01
期刊: Bulletin of the World Health Organization: International Journal of Public Health
影响因子: --
作者:
Ferrand, Rashida;Lowe, Sara;Corbett, Elizabeth L
通讯作者: Corbett, Elizabeth L
DOI: 10.1001/archpedi.159.8.764
发表时间: 2005-08-01
影响因子: --
作者:
Murphy, DA;Belzer, M;Muenz, LR
通讯作者: Muenz, LR