Particulate cancellous marrow crib graft reconstruction of mandibular defects
Particulate cancellous marrow crib graft reconstruction of mandibular defects
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颗粒松质骨髓移植重建下颌骨缺损
DOI：
10.1288/00005537-198012000-00014
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
George Adams
中科院分区：
文献类型：
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作者：
A. Giordano;Dennis Brady;C. Foster;George Adams
从1969年到1978年，明尼苏达大学及其附属医院的耳鼻咽喉科治疗了1000多个下颌骨骨折。大多数患者都得到了成功的治疗，但有17名患者下颌骨严重丢失，导致了更困难的管理问题。骨丢失通常是由于最初的损伤，如枪伤，或继发于骨不连或骨髓炎的并发症。用Vitallium®或钛网床内的颗粒松质骨髓移植(PCM网状移植物)重建下颌骨缺损。1例患者双侧有缺陷，需要2个PCM婴儿床移植。因此，共进行了18例横跨2-12厘米的移植物。成功的衡量标准是下颌稳定，咬合满意，咀嚼、吞咽和发音能力令人满意。在18个移植物中，15个符合这些要求。下颌骨重建成功的几个重要因素包括：充分的固定，口腔内软组织覆盖，外部皮肤覆盖和无张力闭合，以及最佳的口腔内卫生。
Between 1969 and 1978 more than 1000 mandible fractures were treated by the otolaryngology services at the University of Minnesota and affiliated hospitals. Most were successfully treated but 17 patients had significant loss of mandibular bone resulting in a much more difficult management problem. The loss of bone was usually due either to the initial injury such as a gunshot wound or was secondary to the complications of nonunion or osteomyelitis. Particulate cancellous marrow grafts within a Vitallium® or titanium mesh crib (PCM crib graft) were used to reconstruct the mandibular defects. One patient had bilateral defects requiring 2 PCM crib grafts. Thus, 18 grafts spanning defects 2 to 12 cm were performed. Success was measured by a stable mandible with satisfactory occlusion and he ability to chew, swallow and articulate satisfactorally. Of 18 grafts, 15 met these requirements. Several factors important to successful mandibular reconstruction included adequate immobolization, intraoral soft tissue coverage, external skin cover and tension‐free closure and optimal intraoral hygiene.