Persistence of Ebola Virus in Ocular Fluid during Convalescence.
Persistence of Ebola Virus in Ocular Fluid during Convalescence.
复制标题
DOI：
10.1056/nejmoa1500306
复制
发表时间：
2015-06-18
期刊：
影响因子：
--
通讯作者：
Yeh S
中科院分区：
文献类型：
--
作者：
Varkey JB;Shantha JG;Crozier I;Kraft CS;Lyon GM;Mehta AK;Kumar G;Smith JR;Kainulainen MH;Whitmer S;Ströher U;Uyeki TM;Ribner BS;Yeh S
在埃博拉病毒病（EVD）幸存者中，在恢复期可出现包括葡萄膜炎在内的并发症，尽管与埃博拉病毒病相关的葡萄膜炎的发病率和发病机制尚不清楚。我们描述了一位从埃博拉病毒病中康复的患者，随后在康复期间发现患有严重的单侧葡萄膜炎。在埃博拉病毒病发病后14周和病毒血症清除后9周在房水中检测到活扎伊尔埃博拉病毒（EBOV）。
Among the survivors of Ebola virus disease (EVD), complications that include uveitis can develop during convalescence, although the incidence and pathogenesis of EVD-associated uveitis are unknown. We describe a patient who recovered from EVD and was subsequently found to have severe unilateral uveitis during convalescence. Viable Zaire ebolavirus (EBOV) was detected in aqueous humor 14 weeks after the onset of EVD and 9 weeks after the clearance of viremia.