The psychosocial burden of human papillomavirus related disease and screening interventions
The psychosocial burden of human papillomavirus related disease and screening interventions
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DOI：
10.1136/sti.2009.037028
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发表时间：
2009-12-01
影响因子：
3.6
通讯作者：
Garland, S.
中科院分区：
文献类型：
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作者：
Pirotta, M.;Ung, L.;Garland, S.
目标： (i) 评估人乳头瘤病毒 (HPV) 相关生殖器疾病检测或 HPV 相关诊断的社会心理负担； (ii) 将专门设计用于测量 HPV 相关心理社会负担的工具与其他通用生活质量 (QoL) 工具进行比较。方法：横断面设计。研究人员从一家大型三级妇女医院和性健康中心的门诊招募了女性，她们在收到结果后 3 个月内完成了调查：331 名女性，年龄 18-45 岁，宫颈巴氏涂片 (Pap) 结果正常，巴氏涂片结果异常，活检证实宫颈上皮内瘤变 (CIN) 或外生殖器疣 (EGW)。主要结果指标：旨在评估 HPV 的社会心理影响的 HPV 影响概况 (HIP)；两项与健康相关的一般生活质量调查——EuroQoL VAS 和 Sheehan 残疾量表；以及HPV知识调查。结果：有效率78%。研究发现，接受 HPV 相关生殖器疾病筛查或诊断的女性会受到显着的社会心理影响。影响最大的是患有 CIN 2/3 和 EGW 的女性。 HIP 可以最灵敏地检测到这种与 HPV 相关的社会心理影响。相对于一般的生活质量衡量标准，HIP 提供了对 HPV 检测和诊断的全方位心理社会影响的深入了解。 结论：临床医生需要意识到检测或诊断 HPV 相关生殖器疾病（特别是 CIN 2/3 和 EGW）的潜在心理社会影响。与一般生活质量调查相比，HIP 调查是对 HPV 相关生殖器疾病的社会心理影响更为敏感的衡量标准。
Objectives: (i) To assess the psychosocial burden of testing for human papillomavirus (HPV) related genital disease or of a HPV-related diagnosis; (ii) to compare an instrument specifically designed to measure HPV-related psychosocial burden with other generic quality of life (QoL) instruments.Methods: A cross-sectional design. Researchers recruited women from outpatient clinics at a major tertiary women's hospital and a sexual health centre who completed surveys within 3 months of receiving results: 331 women, 18-45 years, who had experienced a normal cervical Papanicolaou (Pap) result, an abnormal Pap result, biopsy confirmed cervical intraepithelial neoplasia (CIN) or external genital warts (EGW). Main outcome measures: the HPV impact profile (HIP) designed to assess the psychosocial impact of HPV; two general health-related QoL surveys-the EuroQoL VAS and the Sheehan disability scale; and a HPV knowledge survey.Results: Response rate was 78%. Significant psychosocial impacts were found for women screened for, or having a diagnosis of, HPV-related genital disease. The largest impact was in women with CIN 2/3 and EGW. This HPV-related psychosocial impact was most sensitively detected with the HIP. Relative to generic measures of QoL, the HIP provided insight into the full range of psychosocial impacts of HPV testing and diagnoses.Conclusions: Clinicians need to be aware of the potential psychosocial impact of testing for or diagnosing HPV-related genital disease, in particular CIN 2/3 and EGW. The HIP survey is a more sensitive measure of the psychosocial impact of HPV-related genital disease than generic QoL surveys.