Parastomal pyoderma gangrenosum: clinical features and management.
Parastomal pyoderma gangrenosum: clinical features and management.
复制标题
造口旁坏疽性脓皮病：临床特征和治疗。
DOI：
10.1067/mjd.2000.104515
复制
发表时间：
2000
影响因子：
13.8
通讯作者：
C. Griffiths
中科院分区：
文献类型：
--
作者：
C. Lyon;C. Lyon;Amanda J. Smith;Amanda J. Smith;M. Beck;M. Beck;G. Wong;G. Wong;C. Griffiths;C. Griffiths
背景
BACKGROUND
The importance of pyoderma gangrenosum (PG) as a cause of ulceration around abdominal stomas is not well recognized.
OBJECTIVE
Our purpose was to describe the incidence, clinical and histologic features, disease associations, and possible risk factors for parastomal PG.
METHODS
A clinic, run by a dermatologist and two stoma nurses, was created. Five hundred patients approached by postal questionnaire were invited to attend if they had skin problems. In addition, local surgical, dermatologic, and nursing services were invited to refer patients with parastomal skin problems. Cases of parastomal PG were identified, investigated, and treated.
RESULTS
The annual incidence of parastomal PG in the questionnaire-based cohort of patients was 0.6% (3 patients). An additional 23 patients with the condition were seen. No consistent hematologic, biochemical, immunologic, microbiological or histologic abnormalities were identified. Local skin damage did not appear to be an important trigger for parastomal PG. The condition is recurrent in one third of cases. Topical tacrolimus (0.3% in carmellose sodium paste) has been effective in 4 patients.
CONCLUSION
Parastomal PG is far more common than previous reports would suggest, and it may be associated with diseases other than inflammatory bowel disease.