The effect of calcium hydroxide on porcine pulp fibroblasts in vitro.
The effect of calcium hydroxide on porcine pulp fibroblasts in vitro.
复制标题
氢氧化钙对体外猪牙髓成纤维细胞的影响。
DOI：
10.1016/s0099-2399(83)80031-4
复制
发表时间：
1983
影响因子：
4.2
通讯作者：
T. Howley
中科院分区：
文献类型：
--
作者：
C. Torneck;H. Moe;T. Howley
用[3 H]TdR掺入法研究Ca（OH）2溶液（0.001137 g/ml）对体外培养的猪牙髓成纤维细胞DNA合成的影响。数据表明，当向培养基中加入0.025 ml Ca（OH）2溶液时，摄取率显著增加。当使用0.050 ml Ca（OH）2溶液时，这种效应不明显。因此，似乎某些浓度的氢氧化钙的存在对牙髓成纤维细胞是促有丝分裂的，而其他的则不是。这些研究结果的意义相对于临床使用的氢氧化钙化合物在牙科治疗进行了讨论。
The effect of Ca(OH)2solution (0.001137 g/ml) on DNA synthesis of porcine pulp fibroblasts in vitro was evaluated by measuring the rate of [3H]TdR uptake. The data indicated that there was a significant increase in the uptake rate when 0.025 ml of the Ca(OH)2solution was added to the culture medium. This effect was not apparent when 0.050 ml of Ca(OH)2solution was used. It appears, therefore, that the presence of certain concentrations of calcium hydroxide are mitogenic for pulp fibroblasts while others are not. The significance of these findings relative to the clinical use of calcium hydroxide compounds in dental therapeutics is discussed.