The sex ratio of siblings of individuals with a history of developmental language disorder
The sex ratio of siblings of individuals with a history of developmental language disorder
复制标题
有发育性语言障碍史的个体的兄弟姐妹的性别比例
DOI：
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发表时间：
2010
期刊：
影响因子：
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通讯作者：
Karen
中科院分区：
文献类型：
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作者：
S. Mouridsen;Karen
摘要有一个很好的记录优势的男性诊断为神经发育障碍。性类固醇对大脑发育的影响被认为是发育心理病理学中性别差异的中介，并被集中体现在“极端男性大脑理论”中。本研究的目的是扩展以往的研究处理极端男性大脑理论和研究的性别比（男性的比例）在兄弟姐妹的469个人与发展性语言障碍（DLD）谁是连续评估在同一诊所在一段时间内的10年。在他们的908个活产兄弟姐妹中，503个是男性，405个是女性。这产生了0.554的性别比，这是显着高于丹麦活产的性别比0.514在同一时期（P = 0.02）。我们的研究结果与男性性激素可能与DLD病因学有关的假设一致。
Abstract There is a well documented predominance of males diagnosed with neurodevelopmental disorders. The influence of sex steroids upon brain development has been suggested to mediate sex differences in developmental psychopathology, and has been epitomized in the ‘extreme male brain theory’. The objective of this study was to extend previous studies dealing with the extreme male brain theory and to study the sex ratio (proportion of males) in the siblings of 469 individuals with a developmental language disorder (DLD) who were consecutively assessed in the same clinic during a period of 10 years. Among their 908 live-born siblings, 503 were males and 405 females. This yields a sex ratio of 0.554, which is significantly higher than the Danish live birth sex ratio of 0.514 over the same period (P = 0.02). Our findings are consistent with the hypothesis that male sex hormones may be implicated in the aetiology of DLD.
责任心是男性化手指长度比例与注意力缺陷/多动障碍（ADHD）之间关联的中介因素。
DOI：
10.1111/j.1469-7610.2009.02065.x
发表时间：
2009
期刊：
Journal of child psychology and psychiatry, and allied disciplines
影响因子：
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作者：
Martel,MichelleM
通讯作者：
Martel,MichelleM