ASSESSMENT OF SUN SENSITIVITY BY QUESTIONNAIRE - VALIDITY OF ITEMS AND FORMULATION OF A PREDICTION RULE
ASSESSMENT OF SUN SENSITIVITY BY QUESTIONNAIRE - VALIDITY OF ITEMS AND FORMULATION OF A PREDICTION RULE
复制标题
DOI：
10.1016/0895-4356(92)90104-u
复制
发表时间：
1992-05-01
影响因子：
7.2
通讯作者：
WEINSTOCK, MA
中科院分区：
文献类型：
--
作者：
WEINSTOCK, MA
阳光敏感性是黑色素瘤、基底细胞癌和皮肤鳞状细胞癌的主要危险因素。流行病学研究中已使用多个变量来测量阳光敏感性。本研究评估了它们的有效性，并将它们结合起来形成了客观测量太阳敏感性的预测规则，即产生可见性变红皮肤 (MED) 所需的紫外线 B 辐射的最小红斑剂量。参与者是 116 名接受光疗的银屑病患者，他们完成了阳光敏感性调查问卷。在评估的 14 个问卷项目中，有 10 个项目与 MED 的相关性超出了基于偶然的预期。最密切的关联是与皮肤类型（菲茨帕特里克），这是一个基于历史晒黑能力和晒伤敏感性的 4 分制等级。未晒黑的皮肤和头发的颜色也是独立的预测因素，并被纳入最终的预测规则中，与 MED 的相关性为 0.55。组合项目可以比任何一个或两个单独的响应变量更准确地预测阳光敏感性，因此可能更适合流行病学研究。
Sun sensitivity is a major risk factor for melanoma, basal cell carcinoma, and squamous cell carcinoma of the skin. Several variables have been used in epidemiologic studies to measure sun sensitivity. The present study assesses their validity and combines them to form a prediction rule for an objective measure of sun sensitivity, the minimal erythema dose of ultraviolet B radiation required to produce visibility reddened skin (MED). Participants were 116 patients with psoriasis presenting for phototherapy who completed a sun sensitivity questionnaire. Of the 14 questionnaire items evaluated, 10 were associated with the MED beyond expectation based on chance. The closest association was with the skin type (of Fitzpatrick), a 4-point scale based on historical ability to tan and susceptibility to sunburn. Color of untanned skin and hair were also independent predictors, and were included in the final prediction rule, which correlated 0.55 with MED. Combining items yields a more accurate predictor of sun sensitivity than any one or two individual response variables, and hence may be preferable for epidemiologic studies.