Impact of implementing an evidence-based definition of enteral nutrition intolerance on nutrition delivery: A prospective, cross-sectional cohort study.
Impact of implementing an evidence-based definition of enteral nutrition intolerance on nutrition delivery: A prospective, cross-sectional cohort study.
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实施基于证据的肠内营养不耐受定义对营养输送的影响：一项前瞻性横断面队列研究。
DOI：
10.1002/ncp.10941
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Martinez,EnidE
中科院分区：
文献类型：
--
作者：
Liauchonak,Siarhei;Hamilton,Susan;Franks,JenniferD;Callif,Charles;Akhondi-Asl,Alireza;Ariagno,Katelyn;Mehta,NileshM;Martinez,EnidE
背景肠内营养不耐受导致的肠内营养中断阻碍了营养的输送。我们的目的是检查是否修改EN不耐受的定义的算法将减少EN中断和改善营养输送危重children.MethodsWe进行了一项横断面队列研究，包括谁被接纳到我们的重症监护室（ICU）的患者>24小时，并收到EN。我们的营养算法中的EN不耐受定义被修改为包括EN不耐受的两种症状。我们比较了时间60% EN充足（EN交付/EN规定的x 100）和EN中断之前和之后，这个intervention.ResultsWe包括150名合格的患者，78和72例患者在实施前和实施后队列，分别。人口统计学和临床特征无显著差异。实施前和实施后队列分别在ICU入院后4（2-5）天和3（2-5）天达到60%的EN充分性（P= 0.59）。实施前队列每例患者的中位中断次数为1（1-2），实施后队列为2（1-3;P= 0.08）。中断的频率，因为EN不耐受在ICU入院的前8天内是17在preimplementation和10在postimplementation cohorts.ConclusionModifying EN不耐受的定义的营养算法没有改变的时间，60% EN充分或EN中断的危重患儿总数。EN不耐受和中断继续限制营养输送。需要研究EN不耐受的最佳定义及其对营养结果的影响。
BackgroundEnteral nutrition (EN) interruptions because of EN intolerance impede nutrient delivery. We aimed to examine whether revising the EN intolerance definition of an algorithm would decrease EN interruptions and improve nutrient delivery in critically ill children.MethodsWe performed a cross‐sectional cohort study including patients who were admitted to our intensive care unit (ICU) for >24 h and received EN. The EN intolerance definition in our nutrition algorithm was modified to include two symptoms of EN intolerance. We compared time to 60% EN adequacy (EN delivered/EN prescribed x 100) and EN interruptions before and after this intervention.ResultsWe included 150 eligible patients, 78 and 72 patients in the preimplementation and postimplementation cohorts, respectively. There were no significant differences in demographics and clinical characteristics. The preimplementation and postimplementation cohorts achieved 60% EN adequacy 4 (2–5) days and 3 (2–5) days after ICU admission, respectively (P= 0.59). The preimplementation cohort had a median of 1 (1–2) interruption per patient and the postimplementation cohort 2 (1–3;P= 0.08). The frequency of interruptions because of EN intolerance within the first 8 days of ICU admission was 17 in the preimplementation and 10 in the postimplementation cohorts.ConclusionModifying the EN intolerance definition of a nutrition algorithm did not change the time to 60% EN adequacy or total number of EN interruptions in critically ill children. EN intolerance and interruptions continue to limit nutrient delivery. Research on the best definition for EN intolerance and its effect on nutrition outcomes is needed.
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影响因子：
120.7
作者：
Reignier, Jean;Mercier, Emmanuelle;Lascarrou, Jean-Baptiste
通讯作者：
Lascarrou, Jean-Baptiste
影响因子：
3.6
作者：
Tume LN;Bickerdike A;Latten L;Davies S;Lefèvre MH;Nicolas GW;Valla FV
通讯作者：
Valla FV
在一项研究危重儿童未进行常规胃残留量测量的试验中确定最佳结果措施。
DOI：
--
发表时间：
2020
期刊：
JPEN - Journal of Parenteral and Enteral Nutrition
影响因子：
--
作者：
L. Tume;B. Arch;K. Woolfall;L. Roper;E. Deja;Ashley P. Jones;L. Latten;H. Eccleson;H. Hickey;N. Pathan;J. Preston;A. Beissel;I. Andrzejewska;C. Gale;F. Valla;J. Dorling
通讯作者：
J. Dorling
影响因子：
6.3
作者：
Blaser, Annika Reintam;Starkopf, Liis;Starkopf, Joel
通讯作者：
Starkopf, Joel
影响因子：
3.1
作者：
Martinez, Enid E.;Bechard, Lori J.;Mehta, Nilesh M.
通讯作者：
Mehta, Nilesh M.