Direct electrochemistry of cytochrome c at gold electrode modified with fumed silica
Direct electrochemistry of cytochrome c at gold electrode modified with fumed silica
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DOI：
10.1002/elan.200503298
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发表时间：
2005-10-01
期刊：
影响因子：
3
通讯作者：
Wang, EK
中科院分区：
文献类型：
--
作者：
Chen, HJ;Wang, YL;Wang, EK
在硅烷单分子膜上自组装的二氧化硅颗粒(FSP)构建的金电极上，获得了马心细胞色素c(Cytc)的直接电化学。在FSPs膜修饰的金电极上，获得了一对清晰且近对称的氧化还原峰。用循环伏安法(CV)和原子力显微镜(AFM)对FSPs膜修饰电极进行了表征，结果表明FSPs为细胞色素C提供了良好的微环境，促进了细胞色素C与金电极之间的直接电子转移，为实现其他蛋白质的直接电化学提供了一种途径。
Direct electrochemistry of horse heart cytochrome c (cytc) has been obtained at a gold electrode constructed by self-assembling turned silica particles (FSPs) onto a silane monolayer. A pair of well-defined and nearly symmetrical redox peaks of cytc is obtained at the FSPs film modified gold electrode. Cyclic voltammetry (CV) and tapping-mode atomic force microscopy (AFM) are used to characterize the FSPs film modified electrode, showing that the FSPs can provide a favorable microenvironment for cytc and facilitate the direct electron transfer between the cytc and the gold electrode, which may propose an approach to realize the direct electrochemistry of other proteins.