Solid-State 1H NMR Studies of Degradable Poly(ethylene oxide) Based Hydrogels
Solid-State 1H NMR Studies of Degradable Poly(ethylene oxide) Based Hydrogels
复制标题
可降解聚环氧乙烷水凝胶的固态 1H NMR 研究
DOI：
10.1002/marc.200400605
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发表时间：
2005
影响因子：
4.6
通讯作者：
P. Lutz
中科院分区：
文献类型：
--
作者：
Kaynoush Naraghi;B. Meurer;P. Lutz
以α，ω-甲基丙烯酰氧基-聚氧化乙烯（PEO）-嵌段-1，3-PDXL-嵌段-PEO大分子单体为单体，通过自由基均聚反应，制备了由两个亲水性聚氧化乙烯（PEO）嵌段和一个短的中心聚1，3-二氧戊环（PDXL）嵌段组成的弹性链水凝胶。已知由于缩醛基团的存在，中心PDXL嵌段对酸性降解敏感。一旦溶胀至平衡，这些水凝胶的特征在于它们的平衡溶胀度和它们的机械性能和网络降解的研究进行。
Hydrogels, the elastic chains of which are constituted of a short central poly(1,3-dioxolane) (PDXL) block surrounded by two hydrophilic poly(ethylene oxide) (PEO) blocks, were obtained by free radical homopolymerization of α,ω-methacryloyioxy PEO-block-1,3-PDXL-block-PEO macromonomers. The central PDXL block is known to be sensitive to acidic degradation due to the presence of acetal groups. Once swollen to equilibrium, these hydrogels were characterized for their equilibrium swelling degree and their mechanical properties and network degradation studies were carried out.