Prosthetic patches for congenital diaphragmatic hernia repair: Surgisis vs Gore-Tex
Prosthetic patches for congenital diaphragmatic hernia repair: Surgisis vs Gore-Tex
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DOI：
10.1016/j.jpedsurg.2005.10.005
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发表时间：
2006-01-01
影响因子：
2.4
通讯作者：
Nobuhara, KK
中科院分区：
文献类型：
--
作者：
Grethel, EJ;Cortes, RA;Nobuhara, KK
目的：先天性腹股沟疝（CDH）的后遗症持续到围产期以后。高达50%的患者随后复发疝或小肠梗阻（SBO）。最近的趋势是使用生物活性假体材料。我们回顾了不同的补丁关闭技术用于CDH修复在我们的机构和他们的关联与这些symptoms.Methods：进行了回顾性分析，152例CDH患者的记录。接受CDH修补术并存活至少30天的新生儿被纳入分析。评价的主要结局为疝复发和SBO。两种类型的假体进行了检查，GoreTex，一种人工材料，和Surgisis，一种生物活性material.Results：十二（44%）的27例Surgisis修复复发疝。45例Gore-Tex修补术患者中有17例（38%）疝复发。每组中另外两名患者出现SBO。疝复发率无显著差异（P> 0.5）。两组的复发时间相似（对数秩，P = 0.75），大多数复发（92%Surgisis，76%Gore-Tex）发生在第一年。结论：新生儿CDH修补修补术后疝复发率和SBO相似，无论使用何种修补材料（Surgisis或Gore-Tex）。(c)2006年爱思唯尔公司All rights reserved.
Purpose: The sequelae of congenital diaphragmatic hernia (CDH) continue well beyond the perinatal period. Up to 50% of these patients have subsequent recurrent herniation or small bowel obstruction (SBO). A recent trend has been toward the use of bioactive prosthetic materials. We reviewed different patch closure techniques used for CDH repair at our institution and their association with these sequelae.Methods: A retrospective review was performed of 152 records for patients with CDH. Newborns that underwent patch repair for CDH and survived for at least 30 days were included in the analysis. Primary outcomes evaluated were recurrent herniation and SBO. Two types of prostheses were examined, GoreTex, an artificial material, and Surgisis, a bioactive material.Results: Twelve (44%) of 27 patients who had Surgisis repair had recurrent herniation. Seventeen (38%) of 45 patients who had a Gore-Tex repair had recurrent herniation. Two additional patients in each group presented with SBO. No significant difference in recurrent herniation rates was observed (P > .5). The time to recurrence was similar in both groups (log-rank, P = .75), with most recurrences (92% Surgisis, 76% Gore-Tex) occurring in the first year.Conclusion: The rates of recurrent herniation and SBO after neonatal prosthetic patch repair of CDH were similar regardless of the prosthetic material used (Surgisis or Gore-Tex). (c) 2006 Elsevier Inc. All rights reserved.