Synchronization of local neural networks in the somatosensory cortex: A comparison of stationary and moving stimuli.
Synchronization of local neural networks in the somatosensory cortex: A comparison of stationary and moving stimuli.
复制标题
体感皮层局部神经网络的同步：静止和移动刺激的比较。
DOI：
10.1152/jn.1999.81.3.999
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发表时间：
1999
期刊：
影响因子：
--
通讯作者：
Alloway,KD
中科院分区：
文献类型：
--
作者：
Roy,S;Alloway,KD
刺激引起的体感皮层局部神经网络同步性的增加：静止和移动刺激的比较。 通过完整的氟烷麻醉猫的初级（SI）体感皮层中的一系列电极记录邻近神经元组的自发反应和刺激诱导的反应。互相关分析用于表征自发活动的协调以及对移动或静止空气射流的外周刺激的反应。尽管仅在记录的单个神经元对中的 10%（880 个中的 88 个）中检测到同步，但多单元响应的互相关分析显示，在 123 个记录的电极对中，64% 的同步水平很高。与自发活动相比，静止和移动的空气喷射都会导致 SI 皮层局部区域同步活动的速率、比例和时间精度显着增加。在通过两种类型的喷气刺激同步的神经元群体中，移动喷气刺激期间同步活动的平均速率显着高于静止喷气刺激期间。在原始互相关图 (CCG) 中，移动空气射流还产生比静止空气射流显着更高的相关系数，但在平移校正 CCG 中却没有。刺激引起的同步的发生率和速率随着记录位点之间的距离而变化。对于相距 ≤300 μm 的位点，80% 的多单元响应在两种类型的空气喷射刺激期间表现出显着的同步水平。对于相隔 ≥500 μm 的位点，只有 37% 的多单元反应通过单次空气喷射的离散刺激实现同步。多单元 CCG 峰半宽度的测量表明，由移动空气射流产生的相关活动的时间变异性比由静止空气射流产生的时间变异性稍小。这些结果表明，在局部 SI 神经元组中，移动刺激比静止刺激产生更高水平的同步，并表明神经元同步可以补充发射率的变化，发射率编码皮肤刺激的强度和其他属性。
Stimulus-induced increases in the synchronization of local neural networks in the somatosensory cortex: a comparison of stationary and moving stimuli. Spontaneous and stimulus-induced responses were recorded from neighboring groups of neurons by an array of electrodes in the primary (SI) somatosensory cortex of intact, halothane-anesthetized cats. Cross-correlation analysis was used to characterize the coordination of spontaneous activity and the responses to peripheral stimulation with moving or stationary air jets. Although synchronization was detected in only 10% (88 of 880) of the pairs of single neurons that were recorded, cross-correlation analysis of multiunit responses revealed significant levels of synchronization in 64% of the 123 recorded electrode pairs. Compared with spontaneous activity, both stationary and moving air jets caused substantial increases in the rate, proportion, and temporal precision of synchronized activity in local regions of SI cortex. Among populations of neurons that were synchronized by both types of air-jet stimulation, the mean rate of synchronized activity was significantly higher during moving air-jet stimulation than during stationary air-jet stimulation. Moving air jets also produced significantly higher correlation coefficients than stationary air jets in the raw cross-correlograms (CCGs) but not in the shift-corrected CCGs. The incidence and rate of stimulus-induced synchronization varied with the distance separating the recording sites. For sites separated by ≤300 μm, 80% of the multiunit responses displayed significant levels of synchronization during both types of air-jet stimulation. For sites separated by ≥500 μm, only 37% of the multiunit responses were synchronized by discrete stimulation with a single air jet. Measurements of the multiunit CCG peak half-widths showed that the correlated activity produced by moving air jets had slightly less temporal variability than that produced by stationary air jets. These results indicate that moving stimuli produce greater levels of synchronization than stationary stimuli among local groups of SI neurons and suggest that neuronal synchronization may supplement the changes in firing rate which code intensity and other attributes of a cutaneous stimulus.