Guillain-Barre Syndrome

Guillain-Barre Syndrome
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DOI:
10.1016/j.pop.2015.01.001
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发表时间:
2015-06-01
期刊:
影响因子:
1.9
通讯作者:
Valadi, Nojan
Valadi, Nojan
中科院分区:
医学4区
文献类型:
--
作者:
Ansar, Vibhuti;Valadi, Nojan

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格林-巴利综合征及其临床变异体是一组进展迅速、可能使人虚弱的神经系统疾病,如果不加以识别或治疗,可能会有显著的发病率/死亡率。最常见的症状包括上肢无力和瘫痪,这可能会进展为呼吸衰竭。诊断是通过实验室检测在临床上做出的。有几种治疗方法可供选择,包括血浆置换和静脉注射免疫球蛋白。大多数病例可以在没有后遗症的情况下消失,但那些没有后遗症的病例可能会留下显著的持续性虚弱。
Guillain-Barre syndrome and its clinical variants are a group of rapidly progressing, potentially debilitating neurologic disorders that may have significant morbidity/mortality if left unrecognized or untreated. The most common symptoms include ascending limb weakness and paralysis, which may progress to respiratory failure. Diagnosis is made clinically with laboratory testing. Several treatment options exist, including plasma exchange and intravenous immunoglobulin administration. Most cases may resolve without sequelae, but those that do not may leave behind significant persistent debility.