Isolation of Bartonella henselae, Bartonella koehlerae subsp. koehlerae, Bartonella koehlerae subsp. bothieri and a new subspecies of B. koehlerae from free-ranging lions (Panthera leo) from South Africa, cheetahs (Acinonyx jubatus) from Namibia and capti
Isolation of Bartonella henselae, Bartonella koehlerae subsp. koehlerae, Bartonella koehlerae subsp. bothieri and a new subspecies of B. koehlerae from free-ranging lions (Panthera leo) from South Africa, cheetahs (Acinonyx jubatus) from Namibia and capti
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汉赛巴尔通体、科勒巴尔通体亚种的分离。
DOI：
10.1017/s0950268816001394
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发表时间：
2016
影响因子：
4.2
通讯作者：
Chomel,BB
中科院分区：
文献类型：
--
作者：
Molia,S;Kasten,RW;Stuckey,MJ;Boulouis,HJ;Allen,J;Borgo,GM;Koehler,JE;Chang,CC;Chomel,BB
巴尔通体是血液和媒介传播的革兰氏阴性细菌，被认为是新兴病原体。全血样本采集自南非的 58 头自由放养狮子 (Panthera leo) 和纳米比亚的 17 头猎豹 (Acinonyx jubatus)。还从圣地亚哥野生动物公园的 11 只猎豹身上采集了血液样本（其中一些猎豹采集了不止一次）。从三只狮子（5%）、一只（6%）纳米比亚猎豹和八只（73%）加利福尼亚猎豹的血液中分离出细菌。狮子巴尔通体分离株被鉴定为 B. henselae（两个分离株）和 B. koehlerae subsp。科勒拉埃。纳米比亚猎豹品系与北美野生猫科动物的分离株很接近，但又不同，集中在 B. henselae 和 B. koehlerae 之间。它应被视为 B. koehlerae 的新亚种。所有加州半圈养猎豹分离株均不同于 B. henselae 或 B. koehlerae subsp。 koehlerae 和纳米比亚猎豹分离物。它们也与从加州山狮 (Felis concolor) 分离的菌株不同，并与 B. koehlerae subsp. 菌株聚集在一起。从加州自由放养的山猫 (Lynx rufus) 中分离出的 Bothieri。因此，这些圈养的猎豹很可能被一种本土菌株感染，而山猫是这种菌株的天然宿主。
Bartonellae are blood- and vector-borne Gram-negative bacteria, recognized as emerging pathogens. Whole-blood samples were collected from 58 free-ranging lions (Panthera leo) in South Africa and 17 cheetahs (Acinonyx jubatus) from Namibia. Blood samples were also collected from 11 cheetahs (more than once for some of them) at the San Diego Wildlife Safari Park. Bacteria were isolated from the blood of three (5%) lions, one (6%) Namibian cheetah and eight (73%) cheetahs from California. The lion Bartonella isolates were identified as B. henselae (two isolates) and B. koehlerae subsp. koehlerae. The Namibian cheetah strain was close but distinct from isolates from North American wild felids and clustered between B. henselae and B. koehlerae. It should be considered as a new subspecies of B. koehlerae. All the Californian semi-captive cheetah isolates were different from B. henselae or B. koehlerae subsp. koehlerae and from the Namibian cheetah isolate. They were also distinct from the strains isolated from Californian mountain lions (Felis concolor) and clustered with strains of B. koehlerae subsp. bothieri isolated from free-ranging bobcats (Lynx rufus) in California. Therefore, it is likely that these captive cheetahs became infected by an indigenous strain for which bobcats are the natural reservoir.