Comparison of the Efficacy of Sub-Tenon versus Intravitreal Triamcinolone Acetonide Injection during Cataract Surgery for Diabetic Macular Edema

Comparison of the Efficacy of Sub-Tenon versus Intravitreal Triamcinolone Acetonide Injection during Cataract Surgery for Diabetic Macular Edema
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DOI:
10.1159/000489716
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发表时间:
2019-01-01
期刊:
影响因子:
2.6
通讯作者:
Yamamoto, Shuichi
Yamamoto, Shuichi
中科院分区:
医学3区
文献类型:
--
作者:
Tatsumi, Tomoaki;Oshitari, Toshiyuki;Yamamoto, Shuichi

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目的:比较糖尿病黄斑水肿(DME)患者白内障手术中注射曲安奈德(STTA)和玻璃体腔注射曲安奈德(IVTA)的疗效。方法:对26例(33眼)DME患者行CS+STTA治疗,并与同期行CS+IVTA治疗的DME患者(27例34眼)进行比较。分别于术前、术后1、3、6个月测量中心凹厚度和最佳矫正视力(BCVA)。结果:STTA和IVTA术后3个月和6个月的BCVA均有明显改善。IVTA组的13只眼和STTA组的21只眼需要其他治疗(p<0.05)。1例IVTA术后眼压升高,行选择性激光小梁成形术。结论:对于CS后DME的治疗,眼科医生应考虑IVTA和STTA的优缺点。(C)2018年S.Karger AG,巴塞尔。
Purpose: We compared the efficacy of sub-Tenon triamcinolone acetonide (STTA) to intravitreal triamcinolone acetonide (IVTA) injections during cataract surgery (CS) for patients with diabetic macular edema (DME). Methods: The medical records of 33 eyes (26 patients) with DME which had undergone CS with STTA were compared to those of 34 eyes (27 patients) with DME which had undergone CS with IVTA. Central foveal thickness and best-corrected visual acuity (BCVA) were measured at the baseline and 1, 3, and 6 months after the surgery. Results: The BCVAs after STTA and IVTA were significantly improved at 3 and 6 months. Thirteen eyes in the IVTA group and 21 eyes in the STTA group required other therapies (p < 0.05). One case developed intraocular pressure elevation after IVTA and underwent selective laser trabeculoplasty. Conclusions: Ophthalmologists should consider the merits and demerits of IVTA and STTA for DME treatment after CS. (C) 2018 S. Karger AG, Basel.