Stereoselective synthesis of the AB-ring fragment of gambieric acid A
Stereoselective synthesis of the AB-ring fragment of gambieric acid A
复制标题
DOI：
10.3987/com-06-s(k)30
复制
发表时间：
2007-04-13
期刊：
影响因子：
0.6
通讯作者：
Sasaki, Makoto
中科院分区：
文献类型：
--
作者：
Fuwa, Haruhiko;Suzuki, Akihiro;Sasaki, Makoto
完成了冈比亚酸A的AB环片段的立体选择性合成，其中(I)用于片段组装的乙酰-醛偶联反应和(Ii)通过非对映选择性溴醚化反应构建四氢呋喃A环作为关键转化。
Stereoselective synthesis of the AB-ring fragment of gambieric acid A has been accomplished, wherein (i) an acetylide-aldehyde coupling for fragment assembly and (ii) construction of the tetrahydrofuran A-ring via a diastereoselective bromoetherification were successfully employed as key transformations.