FEVER OF UNKNOWN ORIGIN - A REVIEW OF 80 PATIENTS FROM THE SHINETSU AREA OF JAPAN FROM 1986-1992

FEVER OF UNKNOWN ORIGIN - A REVIEW OF 80 PATIENTS FROM THE SHINETSU AREA OF JAPAN FROM 1986-1992
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DOI:
10.2169/internalmedicine.33.74
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发表时间:
1994-02-01
期刊:
影响因子:
1.2
通讯作者:
IGUCHI, K
IGUCHI, K
中科院分区:
医学4区
文献类型:
--
作者:
SHOJI, S;IMAMURA, A;IGUCHI, K

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在这项涉及 10 家医院的调查中,我们分析了来自信越地区(长野县和新泻县)的 80 名被观察到不明原因发烧 (FUO) 的日本患者的数据。我们的目标是确定根本原因和相关的诊断方法。其中十四名患者死于基础疾病。 FUO 的病因为感染 43 例,过敏或自身免疫性疾病 13 例,肿瘤 7 例,其他原因 3 例,原因不明 14 例。13 例患者 FUO 为自限性,1 例持续存在。成功用于确定 66 例患者最终诊断的方法包括:临床病程或治疗反应评估 16 例、血清学检测 12 例、细菌学检查 10 例、活检 9 例、细胞学检查 6 例、常规放射学 6 例、尸检 3 例、内窥镜检查 2 例、生化检测 2 例。
In this survey involving 10 hospitals, we analyzed data on 80 Japanese patients from the Shin'etsu area (Nagano-ken and Niigata-ken) who were observed for fever of unknown origin (FUO). Our objectives were to identify the underlying causes and the relevant diagnostic methods. Fourteen of the patients died of the underlying illness. The cause of the FUO was infection in 43 patients, allergic or autoimmune disease in 13, neoplasm in 7, miscellaneous causes in 3, and undetermined in 14. FUO was self-limited in 13 patients and persistent in one patient. Methods successfully used to establish the final diagnosis in 66 patients were: evaluation of the clinical course or response to treatment in 16, serologic tests in 12, bacteriologic studies in 10, biopsy in 9, cytologic examination in 6, conventional radiology in 6, necropsy in 3, endoscopy in 2, and biochemical testing in 2.