Renal blood flow measurements with use of phase-contrast magnetic resonance imaging: Normal values and reproducibility
Renal blood flow measurements with use of phase-contrast magnetic resonance imaging: Normal values and reproducibility
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DOI：
10.1097/01.rvi.0000161144.98350.28
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发表时间：
2005-06-01
影响因子：
2.9
通讯作者：
Mali, WPTRM
中科院分区：
文献类型：
--
作者：
Bax, L;Bakker, CJG;Mali, WPTRM
目的：评估相对比（PC）磁共振成像（MR）测量肾血流量（RBF）的有效性和直接、短期和长期的可重复性。材料和方法：在20名健康志愿者中，在重新定位和不重新定位的情况下重复RBF测量。内部有效性是通过比较总RBF与肾动脉上下主动脉流量的差异来评估的。在19名健康志愿者中，在两个不同的场合进行RBF测量。在40名健康志愿者中，进行RBF测量以评估正常值作为年龄的函数。根据Bland和Altman进行分析。结果：技术成功率为78% ~ 85%。总RBF与主动脉血流率的差异具有良好的一致性（Pearson相关系数为0.72;P = 0.002）。直接重复测量总RBF的平均差异为54 mL/min，变异系数（CV）为17%。对于重新定位的重复测量，总RBF的平均差异为74 mL/min （CV, 23%）。在不同场合的重复测量显示CV值为20%。40名健康志愿者平均总RBF为838 mL/min +/- 244 （SD）。结论：PC MR测量RBF的成功率大于75%。该方法的内部可靠性和流量参数的公平再现对于进一步研究肾动脉磁共振成像至关重要。
PURPOSE: To assess the validity and the direct, short-term, and long-term reproducibility of renal blood flow (RBF) measurements with phase-contrast (PC) magnetic resonance (MR) imaging.MATERIALS AND METHODS: In 20 healthy volunteers, RBF measurements were repeated with and without repositioning. Internal validity was assessed by comparing the total RBF with the difference in aortic flow above and below the renal arteries. In 19 healthy volunteers, RBF measurements were performed at two different occasions. In 40 healthy volunteers, RBF measurements were performed to assess normal values as a function of age. Analyses were performed according to Bland and Altman.RESULTS: The technical success rate ranged from 78% to 85%. Total RBF and the difference in aortic flow rates showed good agreement (Pearson correlation coefficient, 0.72; P =.002). Directly repeated measurements had a mean difference of 54 mL/min in total RBF with a coefficient of variation (CV) of 17%. For repeated measurements with repositioning, the mean difference in total RBF was 74 mL/min (CV, 23%). Repeated measurements on different occasions showed a CV of 20%. The mean total RBF of the 40 healthy volunteers was 838 mL/min +/- 244 (SD).CONCLUSIONS: RBF measurement with PC MR has a success rate greater than 75%. The demonstrated internal reliability of this method and fair reproducibility of the flow parameters is crucial for further studies of the renal artery with MR imaging.