UTE imaging with simultaneous water and fat signal suppression using a time-efficient multispoke inversion recovery pulse sequence.
UTE imaging with simultaneous water and fat signal suppression using a time-efficient multispoke inversion recovery pulse sequence.
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DOI：
10.1002/mrm.25823
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发表时间：
2016-08
影响因子：
3.3
通讯作者：
Du J
中科院分区：
文献类型：
--
作者：
Carl M;Bydder GM;Du J
反演恢复准备超短回波（UTE）的重复时间和反演时间长，往往导致扫描时间过长。我们提出了一种优化的长T2信号抑制方法，其中每次反演准备后获得几个k空间辐条。利用Bloch方程对TI和翻转角度等序列参数进行优化，抑制长T2脂肪和水信号，最大化短T2对比度。对一名健康男性志愿者进行了志愿者成像。利用Silver-Hoult绝热反演脉冲和三维（3D） UTE （3D锥）采集进行反演恢复准备。理论信号曲线与实验测得的兴趣曲线区域基本一致。多辐反转恢复法显示了良好的肌肉和脂肪骨髓抑制，并突出了来自股骨和胫骨皮质的短T2信号。在临床扫描时间内，采用多辐采集的反转恢复3D UTE成像可有效抑制长T2信号，突出短T2信号。理论建模可用于确定序列参数，以优化长T2信号抑制和最大化短T2信号。一名志愿者的实验结果证实了理论预测。
The long repetition time and inversion time with inversion recovery preparation ultrashort echo (UTE) often causes prohibitively long scan times. We present an optimized method for long T2 signal suppression in which several k-space spokes are acquired after each inversion preparation. Using Bloch equations the sequence parameters such as TI and flip angle were optimized to suppress the long T2 fat and water signals and to maximize short T2 contrast. Volunteer imaging was performed on a healthy male volunteer. Inversion recovery preparation was performed using a Silver-Hoult adiabatic inversion pulses together with a three-dimensional (3D) UTE (3D Cones) acquisition. The theoretical signal curves generally agreed with the experimentally measured region of interest curves. The multispoke inversion recovery method showed good muscle and fatty bone marrow suppression, and highlighted short T2 signals such as these from the femoral and tibial cortex. Inversion recovery 3D UTE imaging with multiple spoke acquisitions can be used to effectively suppress long T2 signals and highlight short T2 signals within clinical scan times. Theoretical modeling can be used to determine sequence parameters to optimize long T2 signal suppression and maximize short T2 signals. Experimental results on a volunteer confirmed the theoretical predictions.