Diagnostic accuracy of FNA cytology for diagnosis of salivary gland tumors in pediatric patients
Diagnostic accuracy of FNA cytology for diagnosis of salivary gland tumors in pediatric patients
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DOI：
10.1002/cncy.22162
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发表时间：
2019-07-10
影响因子：
3.4
通讯作者：
Cozzolino, Immacolata
中科院分区：
文献类型：
--
作者：
Ronchi, Andrea;Montella, Marco;Cozzolino, Immacolata
背景唾液腺肿瘤在儿科患者中很少见，包括良性和恶性两种类型。虽然细针吸取细胞学已被广泛应用于成人涎腺肿瘤的诊断，但此类诊断技术在儿童患者中的应用和研究仍然很少。然而，强烈建议对涎腺病变进行术前诊断，以计划正确的手术治疗，并避免过度治疗炎性或反应性病变。方法对一系列接受细针吸取的儿童涎腺病变--包括肿瘤性和非肿瘤性病变--进行了回顾性分析。当可获得时，检索相应的组织学诊断。作者计算了细针吸取在这种临床环境下的诊断敏感性和特异性，并评估了细胞学和组织学之间的诊断一致性。结果共收治34例老年涎腺病变患者。
Background Salivary gland tumors are rare in pediatric patients and include both benign and malignant types. Although fine-needle aspiration cytology is widely used to diagnose salivary gland tumors in adults, such diagnostic techniques in pediatric patients are still poorly applied and studied. Nevertheless, a preoperative diagnostic definition of salivary gland lesions is highly recommended to plan a correct surgical management and to avoid over-treatment of inflammatory or reactive lesions. Methods The authors performed a retrospective analysis on a series of salivary gland lesions-both neoplastic and non-neoplastic-in pediatric patients who underwent fine-needle aspiration. When obtainable, the corresponding histological diagnoses were retrieved. The authors calculated the diagnostic sensitivity and specificity of fine-needle aspiration in this clinical setting and evaluated the diagnostic agreement between cytology and histology. Results The series included 34 cases of salivary gland lesions in patients aged