Attractor dynamics in local neuronal networks.
Attractor dynamics in local neuronal networks.
复制标题
DOI:
10.3389/fncir.2014.00022
复制
发表时间:
2014
影响因子:
3.5
通讯作者:
Longtin A
中科院分区:
文献类型:
--
作者:
Thivierge JP;Comas R;Longtin A
Patterns of synaptic connectivity in various regions of the brain are characterized by the presence of synaptic motifs, defined as unidirectional and bidirectional synaptic contacts that follow a particular configuration and link together small groups of neurons. Recent computational work proposes that a relay network (two populations communicating via a third, relay population of neurons) can generate precise patterns of neural synchronization. Here, we employ two distinct models of neuronal dynamics and show that simulated neural circuits designed in this way are caught in a global attractor of activity that prevents neurons from modulating their response on the basis of incoming stimuli. To circumvent the emergence of a fixed global attractor, we propose a mechanism of selective gain inhibition that promotes flexible responses to external stimuli. We suggest that local neuronal circuits may employ this mechanism to generate precise patterns of neural synchronization whose transient nature delimits the occurrence of a brief stimulus.
登录
查看更多内容
影响因子:
3.7
作者:
Sporns O;Honey CJ;Kötter R
通讯作者:
Kötter R
DOI:
10.1098/rsta.2006.1903
发表时间:
2006-12-15
影响因子:
5
作者:
Coombes, Stephen;Doiron, Brent;Shea-Brown, Eric
通讯作者:
Shea-Brown, Eric
影响因子:
2.4
作者:
SCHUSTER, P;SIGMUND, K;WOLFF, R
通讯作者:
WOLFF, R
DOI:
10.1073/pnas.86.5.1698
发表时间:
1989-03-01
影响因子:
11.1
作者:
GRAY, CM;SINGER, W
通讯作者:
SINGER, W
影响因子:
16.2
作者:
Kim, Jimok;Tsien, Richard W.
通讯作者:
Tsien, Richard W.