The role of beverage congeners in hangover and other residual effects of alcohol intoxication: a review.
The role of beverage congeners in hangover and other residual effects of alcohol intoxication: a review.
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DOI：
10.2174/1874473711003020076
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发表时间：
2010-05
期刊：
影响因子：
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通讯作者：
D. Rohsenow;J. Howland
中科院分区：
文献类型：
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作者：
D. Rohsenow;J. Howland
同系物是指除乙醇以外的少量化合物，在蒸馏和发酵过程中自然存在于酒精饮料中。虽然乙醇本身是宿醉（主观痛苦）和酒精的其他残留影响（认知和行为）的主要来源，但由于其中许多同系物的潜在毒性，尽管它们的量很小，所以它们的作用很有趣。调查研究虽然比较了啤酒、白酒和葡萄酒，但通常没有涉及同系物含量明显不同的饮料影响。少数实验研究表明，最高同系物饮料（波旁威士忌）比基本上没有同系物的饮料（伏特加）导致更严重的宿醉评级，尽管乙醇本身的影响比同系物含量对宿醉的影响要大得多。安全敏感的性能，酒精中毒的前一天晚上（警惕与反应时间;共济失调）的影响，波旁酒与伏特加酒没有区别。研究的缺乏表明，要对这些结果有信心，还需要做更多的工作。
Congeners are minor compounds other than ethanol that occur naturally in alcohol beverages as a result of distilling and fermenting processes. While ethanol itself is the main source of hangover (subjective distress) and other residual effects of alcohol (cognitive and behavioral), the role of the congeners is of interest due to the potential toxicity of many of them despite their minute quantities. Survey studies, while comparing beer to liquor to wine, have generally not addressed beverage effects that clearly differ in congener content. The few experimental studies indicate that the highest congener beverage (bourbon) results in more severe hangover ratings than does the beverage with essentially no congeners (vodka), although ethanol effects per se had a considerably stronger effect on hangover than did congener content. Safety-sensitive performance that was affected by alcohol intoxication the previous night (vigilance with reaction time; ataxia) was not differentially affected by bourbon versus vodka. The paucity of studies indicates more work is needed in order to have confidence in these results.