Ion transport by the cortical and outer medullary collecting tubule.

Ion transport by the cortical and outer medullary collecting tubule.
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离子由皮质和外髓集合管运输。

DOI:
10.1038/ki.1982.200
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发表时间:
1982
影响因子:
19.6
通讯作者:
Stokes,JB
Stokes,JB
中科院分区:
医学1区
文献类型:
--
作者:
Stokes,JB

文献摘要

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解剖和细胞形态学。兔收集小管起源于肾脏表面附近,在髓质射线中穿过皮质,并作为无分支结构穿过外髓质。皮质收集小管(CCT)平均接收6个肾单位的内容物。这些肾元的融合通常发生在集合小管起源的近端。因此,收集小管从皮层的表面部分开始,直到它到达髓质内部,在那里收集小管开始融合,形成越来越大的导管,最终通过乳头尖端。图1显示了集合小管穿过皮层和髓质的示意图。兔皮质和外髓收集小管(OMCT)是无分支的,这有利于用离体肾元段体外灌注技术对其进行检查。
Anatomy and cell morphology. The rabbit collecting tubule originates near the surface of the kidney, descends through the cortex within the medullary rays and traverses the outer medulla as an unbranched structure. The cortical collecting tubule (CCT) receives the contents of an average of 6 nephrons [1]. The fusion of these nephrons generally occurs proximal to the origins of the collecting tubule. Thus, the collecting tubule is unbranched from the superficial portion of the cortex until it reaches the inner medulla where the collecting tubules begin to fuse to form larger and larger ducts eventually exiting through the papillary tip. Figure 1 schematically represents the collecting tubule as it courses through the cortex and medulla. The fact that the cortical and outer medullary collecting tubule (OMCT) in the rabbit are unbranched facilitates their examination using the technique of in vitro perfusion of isolated nephron segments.