Heroin overdose among young injection drug users in San Francisco
Heroin overdose among young injection drug users in San Francisco
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DOI：
10.1016/j.drugalcdep.2005.04.012
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发表时间：
2005-12-12
影响因子：
4.2
通讯作者：
Moss, AR
中科院分区：
文献类型：
--
作者：
Ochoa, KC;Davidson, PJ;Moss, AR
目的：我们寻求确定年轻注射吸毒者（IDU）中海洛因相关的过量的患病率和预测因素：共795 IDU年龄在30岁以下的四个街区在旧金山弗朗西斯科，加州，美国进行了采访。在旧金山弗朗西斯科，利用街头宣传和滚雪球技术，对注射毒品使用者中的艾滋病毒、B型和C型肝炎进行了更广泛的研究，作为研究的一部分，招募了参与者。最近的海洛因过量需要干预的独立预测因素确定使用回归analysis.Results：795注射毒品使用者的年龄在30岁以下，22%（174/795）的参与者报告了海洛因过量在过去的一年。在逐步多元逻辑回归中，近期海洛因过量的独立预测因素是终身监禁超过20个月（比值比（OR）= 2.99，95%置信区间（CI）= 1.52-5.88）;最近3个月内注射过海洛因（OR = 4.89，95% CI = 2.03-11.74）;最近3个月注射可卡因（OR = 1.67，95%CI = 1.14-2.45）最近3个月内注射海洛因混合甲基苯丙胺（OR = 1.74，95% CI = 1.15-2.65）;曾检测过B型或C型肝炎（OR = 1.66每年，CI = 1.09-2.54）且曾目睹他人吸毒过量结论：高监禁程度的个体存在吸毒过量的风险，应将监狱或看守所作为吸毒过量的主要干预场所。需要进一步研究可卡因和安非他明在海洛因相关过量中的作用。(c)2005爱思唯尔爱尔兰有限公司保留所有权利。
Objectives: We Sought to identify prevalence and predictors of heroin-related overdose among young injection drug users (IDU).Methods: A total of 795 IDU under age of 30 years were interviewed in four neighbourhoods in San Francisco, California, USA. Participants were recruited as part of a broader study of HIV, hepatitis B and C among injecting drug users in San Francisco using street outreach and snowball techniques. Independent predictors of recent heroin overdose requiring intervention were determined using regression analysis.Results: Of 795 injecting drug users under age of 30 years, 22% (174/795) of participants reported a heroin overdose in the last year. In stepwise multiple logistic regression, independent predictors of recent heroin overdose were lifetime incarceration exceeding 20 months (odds ratio (OR) = 2.99, 95% confidence interval (CI) = 1.52-5.88); heroin injection in the last 3 months (OR = 4.89, 95% Cl = 2.03-11.74); cocaine injection in the last 3 months (OR = 1.67, 95% Cl = 1.14-2.45) injection of heroin mixed with methamphetamine in the last 3 months (OR = 1.74, 95% CI = 1.15-2.65); ever tested for hepatitis B or C (OR = 1.66 per year, CI = 1.09-2.54) and ever having witnessed another person overdose (OR= 2.89, 95% CI = 1.76-4.73).Conclusions: Individuals with high levels of incarceration are at great risk of overdose, and prison or jail should be considered a primary intervention site. Further research on the role of cocaine and amphetamine in heroin-related overdose is indicated. (c) 2005 Elsevier Ireland Ltd. All rights reserved.