Thromboelastography maximum amplitude predicts postoperative thrombotic complications including myocardial infarction
Thromboelastography maximum amplitude predicts postoperative thrombotic complications including myocardial infarction
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DOI：
10.1213/01.ane.0000155290.86795.12
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发表时间：
2005-06-01
影响因子：
5.7
通讯作者：
Bennett-Guerrero, E
中科院分区：
文献类型：
--
作者：
McCrath, DJ;Cerboni, E;Bennett-Guerrero, E
术后血栓并发症增加住院时间和医疗费用。鉴于高凝状态可能导致血栓性并发症，我们试图确定使用血栓弹性成像的术后血液分析是否可以预测血栓性并发症的发生，包括心肌梗死（MI）。我们前瞻性地招募了240名接受各种外科手术的患者。使用已建立的修订的高盛风险指数对每位患者进行心脏风险评分。术后立即进行血栓弹性成像，测定最大振幅（MA），代表血栓强度。术后血栓形成并发症需要通过诊断试验确认，由盲法观察者评估。10例患者（4.2%）共发生12例术后血栓性并发症。MA增高组血栓性并发症发生率（8 / 95 = 8.4%）显著高于MA增高组（P = 0.0157）
Postoperative thrombotic complications increase hospital length of stay and health care costs. Given the potential for thrombotic complications to result from hypercoagulable states, we sought to determine whether postoperative blood analysis using thromboelastography could predict the occurrence of thrombotic complications, including myocardial infarction (MI). We prospectively enrolled 240 patients undergoing a wide variety of surgical procedures. A cardiac risk score was assigned to each patient using the established revised Goldman risk index. Thromboelastography was performed immediately after surgery and maximum amplitude (MA), representing clot strength, was determined. Postoperative thrombotic complications requiring confirmation by a diagnostic test were assessed by a blinded observer. Ten patients (4.2%) suffered a total of 12 postoperative thrombotic complications. The incidence of thrombotic complications with increased MA (8 of 95 = 8.4%) was significantly (P = 0.0157) more frequent than chat of patients with MA