Testing for Interchangeability of Imaging Tests
Testing for Interchangeability of Imaging Tests
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DOI：
10.1016/j.acra.2014.07.004
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发表时间：
2014-11-01
影响因子：
4.8
通讯作者：
Schoenhagen, Paul
中科院分区：
文献类型：
--
作者：
Obuchowski, Nancy A.;Subhas, Naveen;Schoenhagen, Paul
基本原理和目标：新的测试通常通过与参考标准进行比较来评估其技术和诊断性能。一个有效的参考标准，然而，并不总是可用的，并不需要评估一个新的测试与现有的一个one.Materials和方法的可验证性：要显示可验证性的一个新的测试与现有的测试，一个比较新的和现有的测试诊断之间的差异与现有的测试诊断之间的差异在几个场合。我们用两项研究说明了可验证性的测试。在经导管主动脉瓣置换研究中，我们测试了半自动分析是否可以与三维计算机断层扫描（CT）图像的手动重建互换使用。在femorocapulate撞击的患者，我们测试是否磁共振成像（MRI）可以取代CT测量髋臼version.Results：虽然半自动化的方法同意经常与手动测量主动脉瓣的大小（87.6%），互换半自动化的方法与手动测量的专家将导致1.7%-12.2%的频率增加的分歧。互换MRI CT测量髋臼版本将导致2.0度到3.1度的角度测量的差异超过我们预期看到的差异与CT alternates.Conclusions：一个新的和现有的测试之间的协议或相关性的测试是热足够的证据，一个新的测试的性能。可在没有参比标准品的情况下进行可重复性的正式评价。
Rationale and Objectives: New teste at typically assessed by estimating their technical and diagnostic performance through comparisons with a reference standard. A valid reference standard, however; is not always available and is not required for assessing the interchangeability of a new test with an existing one.Materials and Methods: To Show interchangeability of a new test with an existing test, one compares the differences in diagnoses between the hew and existing tests to differences between diagnoses made with the existing test on Several occasions. We illustrate the test for interchangeability with two studies In a transcatheter aortic valve replacement study, we test whether semiautomated analysis can be used interchangeably with manual reconstructions from three-dimensional computed tomography (CT) images. In patients with femoroacetabular impingement, we test whether magnetic resonance imaging (MRI) can replace CT to measure acetabular version.Results: Although the semiautomated method agreed often with the manual measurement of aortic valve-size (87.6%), interchanging the semiautomated method with manual measurements by an expert would lead to a 1.7%-12.2% increase in the frequency of disagreement. Interchanging MRI for CT to measure acetabular version would lead to differences in angle measurements of 2.0 degrees to 3.1 degrees in excess of the differences we would expect to see with CT alone.Conclusions: Testing for agreement or correlation between a new and an existing test is hot sufficient evidence of the performance of a new test. A formal evaluation of interchangeability can be conducted in the absence of a reference standard.