Magnetic resonance elastography of the plantar fat pads - Preliminary study in diabetic patients and asymptomatic volunteers
Magnetic resonance elastography of the plantar fat pads - Preliminary study in diabetic patients and asymptomatic volunteers
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DOI：
10.1097/00004728-200603000-00031
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发表时间：
2006-03-01
影响因子：
1.3
通讯作者：
Weaver, J
中科院分区：
文献类型：
--
作者：
Cheung, YY;Doyley, M;Weaver, J
目的：为了测试的可行性，应用磁共振弹性成像（MRE）技术映射的弹性模量的足底脂肪垫在糖尿病和nondiabetic subjects.Methods：一个原型米泽成像装置被用来产生定量地图的足跟脂肪垫在一个试点研究的12名志愿者和4例糖尿病神经病变。结果：成功地建立了足跟脂肪垫的磁共振弹性图，正常人和糖尿病患者的平均测量值分别为4.85和5.26kPa。结论：在足底脂肪垫上进行磁共振弹性成像并产生弹性图是可行的。糖尿病患者脂肪垫变硬的趋势表明，脂肪垫在性质上是不同的。磁共振弹性成像技术为在体软组织的无创力学研究提供了巨大的潜力。
Objective: To test the feasibility of applying the magnetic resonance elastography (MRE) technique to map the elastic modulus of the plantar fat pads in diabetic and nondiabetic subjects.Methods: A prototype MIZE imaging apparatus was used to produce quantitative maps of the heel fat pad in a pilot study of 12 volunteers and 4 patients with diabetes with neuropathy. Anatomic images corresponding to MIZE maps allowed precise selection of regions of interest in the fat,Results: Magnetic resonance elastograms of the heel fat pads were Successfully created; mean measurements in the volunteers and the diabetic patients were 4.85 and 5.26 kPa, respectively.Conclusion: It is feasible to perforin MRE on the plantar fat pads and to produce elasticity maps. The trend toward stiffer fat pads, as demonstrated in patients with diabetes, suggests that the fat pads were qualitatively different. Magnetic resonance elastography offers great potential to investigate the mechanical properties of soft tissues in vivo noninvasively.