INHIBITORY EFFECTS OF ROOIBOS TEA, ASPALATHUS-LINEALIS, ON X-RAY-INDUCED C3H10T1/2 CELL-TRANSFORMATION
INHIBITORY EFFECTS OF ROOIBOS TEA, ASPALATHUS-LINEALIS, ON X-RAY-INDUCED C3H10T1/2 CELL-TRANSFORMATION
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DOI：
10.1016/0304-3835(94)90344-1
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发表时间：
1994-02-28
期刊：
影响因子：
9.7
通讯作者：
OKUMURA, Y
中科院分区：
文献类型：
--
作者：
KOMATSU, K;KATOR, K;OKUMURA, Y
路易波士茶提取物能抑制X射线诱导的小鼠C3 H10 T1/2细胞的致癌性转化。随着浸提液浓度的增加，转化率降低，因此在浸提液浓度为10%时，转化率与自发水平相似。抑制作用也取决于浸提液的处理时间，在整个孵育期间存在时抑制作用最大。相反，等氧浓度的绿色茶提取物对转化发生率没有可检测的影响。
Oncogenic transformation of mouse C3H10T1/2 cells induced by X-rays was suppressed in the presence of extract of Rooibos tea, Aspalathus linealis. Transformation was reduced with increased concentration of the extract, so that at an extract concentration of 10%, transformation incidence was similar to the spontaneous level. Suppression was also dependent on treatment time with the extract and was maximal when present during the entire incubation period. In contrast, green tea extract at an equitoxic concentration showed no detectable effect on transformation incidence.