Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)
Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)
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DOI：
10.1093/humrep/deh098
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发表时间：
2004-01-01
影响因子：
6.1
通讯作者：
Lobo, R
中科院分区：
文献类型：
--
作者：
Fauser, BCJM;Chang, J;Lobo, R
自1990年NIH主办的多囊卵巢综合征（PCOS）会议以来，人们已经认识到该综合征包括比原始诊断标准定义的更广泛的卵巢功能障碍的体征和症状。2003年鹿特丹共识研讨会得出结论，PCOS是一种卵巢功能障碍综合征，沿着高雄激素血症和多囊卵巢（PCO）形态的主要特征。PCOS仍然是一种综合征，因此，没有单一的诊断标准（如高雄激素血症或PCO）足以用于临床诊断。其临床表现可能包括：月经不调，雄激素过多的迹象，肥胖。胰岛素抵抗和血清LH水平升高也是PCOS的常见特征。PCOS与2型糖尿病和心血管事件的风险增加有关。
Since the 1990 NIH-sponsored conference on polycystic ovary syndrome (PCOS), it has become appreciated that the syndrome encompasses a broader spectrum of signs and symptoms of ovarian dysfunction than those defined by the original diagnostic criteria. The 2003 Rotterdam consensus workshop concluded that PCOS is a syndrome of ovarian dysfunction along with the cardinal features hyperandrogenism and polycystic ovary (PCO) morphology. PCOS remains a syndrome and, as such, no single diagnostic criterion (such as hyperandrogenism or PCO) is sufficient for clinical diagnosis. Its clinical manifestations may include: menstrual irregularities, signs of androgen excess, and obesity. Insulin resistance and elevated serum LH levels are also common features in PCOS. PCOS is associated with an increased risk of type 2 diabetes and cardiovascular events.