Transplantation of pig metanephroi
Transplantation of pig metanephroi
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DOI：
10.1097/00002480-200301000-00008
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发表时间：
2003-01-01
期刊：
影响因子：
4.2
通讯作者：
Hammerman, MR
中科院分区：
文献类型：
--
作者：
Rogers, SA;Talcott, M;Hammerman, MR
为了确定猪后肾是否在同种异体移植或异种移植后生长和分化，跨越高度不同的屏障，我们将来自胚胎第28天（E28）猪胚胎的后肾植入单侧肾切除的成年猪或C57 Bl/6 J小鼠（宿主）的网膜中。一些小鼠宿主接受了抗CD 45 RB、抗CD 154和抗CD 11 a（共刺激阻断）。E28猪后肾
To determine whether pig metanephroi grow and differentiate after allotransplantation or xenotransplantation across a highly disparate barrier, we implanted metanephroi from embryonic day 28 (E28) pig embryos into the omentum of unilaterally nephrectomized adult pigs or C57Bl/6J mice (hosts). Some mouse hosts received anti-CD45RB, anti-CD154, and anti-CD11a (costimulatory blockade). E28 pig metanephroi were