High dynamic range 3D motion tracking using circular scans with optical coherence tomography.
High dynamic range 3D motion tracking using circular scans with optical coherence tomography.
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DOI：
10.1364/boe.493725
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发表时间：
2023-07
影响因子：
3.4
通讯作者：
Senyue Hao;M. Amaral;Chao Zhou
中科院分区：
文献类型：
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作者：
Senyue Hao;M. Amaral;Chao Zhou
来自心跳、呼吸或蠕动等来源的运动伪影通常会降低活体对象的显微图像或视频质量。我们开发了一种使用圆形光学相干断层扫描（OCT）扫描来跟踪生物样本的横向和轴向运动的方法，其速度范围从每秒几微米到每秒几厘米。我们通过自适应控制圆形扫描模式设置并应用帧间和帧内分析来实现对样本运动的幅度和方向的快速、高精度测量。这些测量是通过反馈控制进行主动运动补偿的基础，用于未来体内微观和宏观成像应用。
Motion artifacts, from such sources as heartbeats, respiration, or peristalsis, often degrade microscopic images or videos of live subjects. We have developed a method using circular optical coherence tomography (OCT) scans to track the transverse and axial motion of biological samples at speeds ranging from several micrometers per second to several centimeters per second. We achieve fast and high-precision measurements of the magnitude and direction of the sample's motion by adaptively controlling the circular scan pattern settings and applying interframe and intraframe analyses. These measurements are the basis of active motion compensation via feedback control for future in vivo microscopic and macroscopic imaging applications.