MULTIPLE ORGAN SYSTEM FAILURE AND INFECTION IN ADULT RESPIRATORY-DISTRESS SYNDROME
MULTIPLE ORGAN SYSTEM FAILURE AND INFECTION IN ADULT RESPIRATORY-DISTRESS SYNDROME
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DOI：
10.7326/0003-4819-99-3-293
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发表时间：
1983-01-01
影响因子：
39.2
通讯作者：
JOHANSON, WG
中科院分区：
文献类型：
--
作者：
BELL, RC;COALSON, JJ;JOHANSON, WG
对37例成人呼吸窘迫综合征的连续幸存者和47例尸检的连续非幸存者进行了多器官系统衰竭和感染的评估。中枢神经系统、凝血系统、内分泌系统、胃肠系统和肾脏系统的衰竭在所有患者中都很常见，但在死亡患者中更为常见。46名非幸存者和22名幸存者发生了重大感染。所有具有临床确定感染部位的菌血症患者均存活；所有没有临床确定感染部位的菌血症患者均死亡。后一组的尸检结果显示感染需要手术引流才能完全治疗。临床脓毒症患者，但没有菌血症或明确的感染部位尸检显示为肺炎。多器官系统衰竭在感染（93%）患者中比未感染（47%）患者更常见。成人呼吸窘迫综合征患者感染的有力评估和治疗可能提高生存率。
The role of multiple organ system failure and infection was evaluated in 37 consecutive survivors of adult respiratory distress syndrome and 47 consecutive nonsurvivors on whom autopsies were done. Failure of the CNS, coagulation, endocrine, gastrointestinal and renal systems was common in all patients, but was more frequent in those who died. Major infections occurred in 46 nonsurvivors and 22 survivors. All patients with bacteremia who had a clinically identified site of infection survived; all patients with bacteremia without a clinically identified infection site died. Autopsy results of the latter group showed infections requiring surgical drainage for complete therapy. Patients clinically septic, but without bacteremia or a clear infection site were shown at autopsy to have pneumonia. Multiple organ system failure was more common in infected (93%) than noninfected (47%) patients. Vigorous evaluation and treatment of infection in patients with the adult respiratory distress syndrome may improve survival.