Polarization sensitive optical coherence tomography in equine bone
Polarization sensitive optical coherence tomography in equine bone
复制标题
马骨的偏振敏感光学相干断层扫描
DOI：
10.1117/12.808858
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发表时间：
2009
期刊：
影响因子：
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通讯作者：
S. Matcher
中科院分区：
文献类型：
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作者：
J. Jacobs;S. Matcher
光学相干断层扫描（OCT）已被用于成像马骨样本。OCT和偏振敏感OCT（PS-OCT）图像的马骨样本，脱矿之前和之后，。使用一种新的方法，在不同的照明角度下拍摄一系列图像，在样本的一个部位确定组织内胶原蛋白的极角和真实双折射。这些图像是在骨骼经过脱矿过程之前和之后拍摄的。图像显示脱矿后深度穿透的改善，允许更好地可视化骨的内部结构和胶原蛋白的光学取向。对骨的真实双折射进行了定量测量;真实双折射在脱矿前为1.9x10-3，在脱矿后增加到2.7x10-3。然而，测定的胶原纤维取向在脱矿之前和之后保持相同。骨的研究在组织工程领域是广泛的，其中对内部结构的理解是必不可少的。骨中的OCT和通过脱矿作用改善的深度穿透，为骨分析提供了一种有用的方法。
Optical coherence tomography (OCT) has been used to image equine bone samples. OCT and polarization sensitive OCT (PS-OCT) images of equine bone samples, before and after demineralization, are presented. Using a novel approach, taking a series of images at different angles of illumination, the polar angle and true birefringence of collagen within the tissue is determined, at one site in the sample. The images were taken before and after the bones were passed through a demineralization process. The images show an improvement in depth penetration after demineralization allowing better visualization of the internal structure of the bone and the optical orientation of the collagen. A quantitative measurement of true birefringence has been made of the bone; true birefringence was shown to be 1.9x10-3 before demineralization increasing to 2.7x10-3 after demineralization. However, determined collagen fiber orientation remains the same before and after demineralization. The study of bone is extensive within the field of tissue engineering where an understanding of the internal structures is essential. OCT in bone, and improved depth penetration through demineralization, offers a useful approach to bone analysis.
影响因子：
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作者：
HEE, MR;IZATT, JA;FUJIMOTO, JG
通讯作者：
FUJIMOTO, JG