Effect of Nanoparticles on Biofilm-Growth Disruption: Silver and Platinum Nanoparticles with an Identical Capping Agent
Effect of Nanoparticles on Biofilm-Growth Disruption: Silver and Platinum Nanoparticles with an Identical Capping Agent
复制标题
纳米颗粒对生物膜生长破坏的影响：具有相同封端剂的银和铂纳米颗粒
DOI：
10.11344/nano.10.61
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Honda Y.
中科院分区：
文献类型：
--
作者：
9.Hashimoto M;Honda Y.
许多类型的金属纳米颗粒（NPs）越来越多地可用作牙科材料。本研究评价了银纳米粒子（AgNPs）和铂纳米粒子（PtNPs）对变形链球菌（S. mutans）。两种类型的纳米粒子，稳定的聚乙烯吡咯烷酮（PVP），它具有负表面电荷，在这项研究中使用。本研究评估了具有两种不同的核心金属组合物（Ag和Pt）和相同的表面封端剂（PVP）的特定NP对初始生物膜生长的破坏的影响。这是通过生物膜形成试验和透射电子显微镜的微形态学检查来实现的。PtNPs抑制了S.然而，在AgNP的情况下没有发现抑制作用。观察到PtNP粘附到细菌表面;然而，在AgNP的情况下没有观察到粘附。我们推测纳米粒与S.变形杆菌对生长期间的生物膜形成具有抑制作用。
Many types of metal nanoparticles (NPs) are increasingly available for use as dental materials. The study evaluated the biofilm-growth inhibitory effects of silver NPs (AgNPs) and platinum NPs (PtNPs) against Streptococcus mutans (S. mutans). Two types of NPs, stabilized by polyvinylpyrrolidone (PVP), which has a negative surface charge, were used in this study. This study evaluated the effects of specific NPs, having two different core-metal compositions (Ag and Pt) and an identical surface-capping agent (PVP), on the disruption of initial biofilm growth. This was achieved using a biofilm-forming assay, and micromorphological examinations using a transmission electron microscope. The PtNPs inhibited a biofilm growth against S. mutans; however, no inhibitory effect was found in the case of the AgNPs. It was observed that the PtNPs adhered to the bacteria surface; however, no adhesion was observed in the case of the AgNPs. We speculate that the attachment of the NPs to S. mutans has an inhibitory effect on the biofilm formation during growth.