Update on the Native Kidney Biopsy: Core Curriculum 2019
Update on the Native Kidney Biopsy: Core Curriculum 2019
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DOI：
10.1053/j.ajkd.2018.10.011
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发表时间：
2019-03-01
影响因子：
13.2
通讯作者：
Moeckel, Gilbert W.
中科院分区：
文献类型：
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作者：
Luciano, Randy L.;Moeckel, Gilbert W.
肾活检是一种宝贵的工具，自 20 世纪 50 年代初以来已成为诊断病理性肾脏疾病的金标准。多年来，免疫组织学和超微结构显微镜技术已经得到改进，并且比仅通过简单的光学显微镜获得的信息能够提供更多关于肾脏疾病的病因和分类的信息。肾活检已成为获取关键信息的首选方法，这些信息可与血清学、泌尿和基因检测结合使用，以诊断各种急性和慢性肾脏疾病。肾活检程序的风险相对较低，并能提供大量信息。潜在的并发症包括需要输血的出血、肉眼血尿、动静脉瘘形成和肾周血肿等。经皮肾活检通常使用实时超声或计算机断层扫描成像进行。本核心课程简要概述了肾活检的历史，然后讨论了适应症、并发症和具体的程序方面。
The kidney biopsy is an invaluable tool that has become the gold standard for the diagnosis of pathologic kidney diseases since the early 1950s. Throughout the years, immunohistologic and ultrastructural microscopy techniques have improved and provide more information on the cause and classification of kidney diseases than that available from simple light microscopy alone. Kidney biopsy has become a preferred method to obtain critical information that can be used in conjunction with serologic, urinary, and genetic testing to diagnose a variety of kidney diseases, both acute and chronic. The kidney biopsy procedure carries relatively low risk and yields substantial information. Potential complications include bleeding requiring transfusion, gross hematuria, arteriovenous fistula formation, and perinephric hematoma, among others. Percutaneous kidney biopsies are typically performed using real-time ultrasound or computed tomographic imaging. This Core Curriculum briefly outlines the history of the kidney biopsy, then discusses indications, complications, and specific procedural aspects.