Development of cochlear active mechanisms in humans differs between gender
Development of cochlear active mechanisms in humans differs between gender
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DOI：
10.1016/s0304-3940(96)13226-2
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发表时间：
1996-12-06
影响因子：
2.5
通讯作者：
Collet, L
中科院分区：
文献类型：
--
作者：
Morlet, T;Perrin, E;Collet, L
尽管在妊娠第三期早期就开始发挥功能，但人类听觉系统表现出持续的成熟，以前认为这主要发生在神经水平上。外毛细胞的电动特性似乎对听力敏感性和频率选择性有很大贡献，并导致耳声发射（OAE）的产生。本报告证明了耳蜗功能出现后耳蜗主动机制（即终末器官水平）的持续发展，如 OAE 所反映的那样。还报告了显着的性别差异，对应于最近观察到的耳蜗长度的两性差异以及在成人中观察到的性别差异的先兆。版权所有 (C) 1996 Elsevier Science Ireland Ltd.
Despite onset of function early during the third term of gestation, the human auditory system demonstrates continued maturation, thought previously to occur primarily at the neural level. The electromotile properties of outer hair cells appear to contribute substantially to hearing sensitivity and frequency selectivity and lead to the generation of otoacoustic emissions (OAEs). This report demonstrates continued development of cochlear active mechanisms (i.e. end-organ level) after onset of cochlear function, as reflected by OAEs. Significant gender differences also are reported, corresponding to recently observed intersex differences in cochlear length and precursory to gender differences observed in the adult. Copyright (C) 1996 Elsevier Science Ireland Ltd.