Effects of cholecystokinin peptides on digestive enzymes in killifish in vivo.
Effects of cholecystokinin peptides on digestive enzymes in killifish in vivo.
复制标题
缩胆囊素肽对鳉鱼体内消化酶的影响。
DOI：
10.1016/0300-9629(88)90849-3
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Patton,JS
中科院分区：
文献类型：
--
作者：
Honkanen,RE;Crim,JW;Patton,JS
1.在无胃鳉（Fundulus heteroclitus）中检测了胆囊收缩素样肽引起脂肪酶分泌的能力。2.八肽胆囊收缩素，雨蛙素，和nonsulfated雨蛙素刺激脂肪酶分泌在体内，雨蛙素和nonsulfated雨蛙素是最有效的肽测试。3.卡巴胆碱不能诱导脂肪酶分泌，阿托品不能抑制肽刺激的脂肪酶分泌。4.这些数据表明，消化酶分泌构成了CCK进化的原始作用。
1. The abilities of cholecystokinin-like peptides to elicit lipase secretion were examined in the stomachless killifish, Fundulus heteroclitus. 2. Cholecystokinin octapeptide, caerulein, and nonsulfated caerulein stimulated lipase secretion in vivo, with caerulein and nonsulfated caerulein being the most potent peptides tested. 3. Lipase secretion was not induced by carbachol, and peptide stimulated lipase secretion was not inhibited by atropine. 4. These data suggest digestive enzyme secretion constitutes an evolutionary primitive role for CCK.