Sampling variability of the Kunst-Mackenbach relative index of inequality

Sampling variability of the Kunst-Mackenbach relative index of inequality
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DOI:
10.1136/jech.56.10.762
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发表时间:
2002-10-01
影响因子:
6.3
通讯作者:
Berry, G
Berry, G
中科院分区:
医学2区
文献类型:
--
作者:
Hayes, LJ;Berry, G

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研究目的:推导出计算相对不平等指数的置信限的方法,该指数由Kunst和Mackenbach定义为衡量社会经济地位对不利健康指数(如死亡率)影响的指标。该方法可用于记录在一个连续的规模上的健康结果,作为泊松计数或作为一个二项式variable.Results和结论:的置信限取决于抽样变异的平均死亡率和斜率的回归线的死亡率的社会经济地位规模变量。连续健康结果的最佳方法是基于Fieller定理,但通过将回归线斜率的置信限代入指数计算公式或使用指数对数变换的方差,可以获得良好的近似值。最后一种方法是最适合的建设显着性测试比较指标。死亡率可能在统计学上显著偏离线性,但这并不意味着线性关系不适当,主要决定是是否将置信限基于回归分析得出的斜率的常规标准误,还是使用死亡率估计值的标准差。
Study objective: To derive methods of calculating confidence limits for the relative index of inequality, defined by Kunst and Mackenbach as a measure of the influence of socioeconomic status on an adverse health index, such as mortality rate. The methods may be used for a health outcome recorded on a continuous scale, as a Poisson count or as a binomial variable.Results and Conclusion: The confidence limits depend on the sampling variability of both the mean mortality rate and the slope of the regression line of mortality on the socioeconomic status scale variable. The best method for a continuous health outcome is based on Fieller's theorem but a good approximation is obtained by substituting the confidence limits for the slope of the regression line into the formula for the calculation of the index, or by using the variance of the logarithmic transform of the index. The last method is the most appropriate for the construction of significance tests comparing indices. The mortality rates may show statistically significant departure from linearity, while not suggesting that a linear relation is inappropriate, and the main decision is whether to base the confidence limits on the conventional standard error of the slope derived from the regression analysis or whether to use the standard deviation of the estimates of mortality rates.