Organ-on-a-Chip

Organ-on-a-Chip
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DOI:
10.35493/medu.43.26
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发表时间:
2023-04
期刊:
The Meducator
影响因子:
--
通讯作者:
A. McCracken;Raymond Qu
A. McCracken;Raymond Qu
中科院分区:
其他
文献类型:
--
作者:
A. McCracken;Raymond Qu

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简介 器官芯片 (OoC) 是生物技术的一个新分支,具有提高生物医学研究效率的潜力,特别是在药物发现方面。1 与动物药物测试、塑料孔板和临床试验前的简单测定等传统方法相比,OoC 模仿了人体器官和组织的复杂功能。2 尽管这项技术需要进一步完善才能有效补充动物模型,但它在加速药物发现从实验室到临床的流程方面显示出巨大的前景。1生物技术蓝图
INTRODUCTION Organ-on-a-chip (OoC) is a novel branch of biotechnology with the potential to improve the efficiency of biomedical research, particularly in drug discovery.1 In contrast to conventional methods like animal drug testing, plastic well plates, and simple assays before clinical trials, OoCs mimic the complex functions of human organs and tissues.2 Although this technology requires further refinement before it can effectively complement animal models, it shows great promise in accelerating the bench-to-bedside pipeline of drug discovery.1 BIOTECH BLUEPRINT