Decreased filaggrin-2 expression in the epidermis in a case of pityriasis rotunda.
Decreased filaggrin-2 expression in the epidermis in a case of pityriasis rotunda.
复制标题
圆形糠疹病例表皮中 filaggrin-2 的表达减少。
DOI：
10.1111/ced.12716
复制
发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Shimizu T.
中科院分区：
文献类型：
--
作者：
Makino T;Mizawa M;Seki Y;Hayashi M;Shimizu T.
圆形糠疹(PR)是一种罕见的角化性疾病，以圆形斑块为特征，主要位于躯干和四肢，呈高或低色斑。1 PR的病因尚不清楚。我们报告了一种新的微丝蛋白样蛋白，微丝蛋白-2，在PR皮损中表达。(A)(B)(D)(C)(E)(F)
Pityriasis rotunda (PR) is a rare keratinizing disorder, characterized as round patches presenting as hyper-or hypopigmented plaques, mainly on the trunk and limbs. 1 The aetiology of PR remains unknown. We report expression of a novel filaggrin-like protein, filaggrin-2, in a skin lesion of PR.(a)(b)(d)(c)(e)(f)