IMPROVEMENT OF NLCKEL CATALYST FOR ENANTIOFACE-DIFFERENTIATING (ASYMMETRIC) HYDROGENATION OF METHYL ACETOACETATE
IMPROVEMENT OF NLCKEL CATALYST FOR ENANTIOFACE-DIFFERENTIATING (ASYMMETRIC) HYDROGENATION OF METHYL ACETOACETATE
复制标题
乙酰乙酸甲酯对映异构（不对称）加氢的 NLCKEL 催化剂的改进
DOI：
10.1246/cl.1977.1131
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发表时间：
1977
影响因子：
1.6
通讯作者：
IzumiYoshiharu
中科院分区：
文献类型：
--
作者：
HaradaTadao;OnakaShinji;TaiAkira;IzumiYoshiharu
在酒石酸改性镍催化剂上乙酰乙酸甲酯加氢制光学活性3-羟基丁酸甲酯的反应中，铝或相关金属化合物的存在对反应产率有不利影响。使用还原的氧化镍代替阮内镍导致良好的光学产率（最大光学产率，85%）。
Among the factors affecting the optical yield of hydrogenation of methyl acetoacetate to optically active methyl 3-hydroxybutyrate with tartaric acid-modified nickel catalysts, the presence of aluminium or related metal compound on the catalysts was found to be the unfavorable one. The use of reduced nickel oxide instead of Raney nickel resulted in a good optical yield (maximum optical yield, 85%).