Distribution and phylogenetic significance of 27-hydroxy-octacosanoic acid in lipopolysaccharides from bacteria belonging to the alpha-2 subgroup of Proteobacteria.
Distribution and phylogenetic significance of 27-hydroxy-octacosanoic acid in lipopolysaccharides from bacteria belonging to the alpha-2 subgroup of Proteobacteria.
复制标题
属于变形菌门 α-2 亚组的细菌脂多糖中 27-羟基-二十八烷酸的分布和系统发育意义。
DOI：
10.1099/00207713-41-2-213
复制
发表时间：
1991
期刊：
影响因子：
--
通讯作者：
Mayer,H
中科院分区：
文献类型：
--
作者：
Bhat,UR;Carlson,RW;Busch,M;Mayer,H
筛选来自属于变形菌纲α-2亚组的许多细菌的脂多糖（LPS）中是否存在27-羟基-二十八烷酸（27-OH-28：0）。除了少数例外，大多数细菌在其脂质A组分中含有27-OH-28：0。此外，一些细菌含有其他的n-2-羟基化的长链脂肪酸迄今没有报道。27-OH-28：0的分布仅限于α-2亚组。来自其他亚组（β和γ亚组）成员的LPS，包括一些充分表征的肠细菌LPS，缺乏27-OH-28：0。我们的研究结果表明，N-2-羟基化的长链脂肪酸在LPS的存在下，可能会被用作一个化学系统发生标记。
Lipopolysaccharides (LPSs) from a number of bacteria belonging to the alpha-2 subgroup of the class Proteobacteria were screened for the presence of 27-hydroxy-octacosanoic acid (27-OH-28:0). With few exceptions, most of the bacteria contained 27-OH-28:0 in their lipid A fractions. In addition, some of the bacteria contained other n-2-hydroxylated long-chain fatty acids hitherto not reported. The distribution of 27-OH-28:0 was restricted to the alpha-2 subgroup. LPSs from members of the other subgroups (the beta and gamma subgroups), including some well-characterized enterobacterial LPSs, were devoid of 27-OH-28:0. Our results indicate that the presence of n-2-hydroxylated long-chain fatty acids in LPSs might be used as a chemophylogenetical marker.