Autologous mononuclear bone marrow cells during reparative regeneratrion after acute myocardial infarction

Autologous mononuclear bone marrow cells during reparative regeneratrion after acute myocardial infarction
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DOI:
10.1007/s10517-006-0043-1
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发表时间:
2005-11-01
影响因子:
0.7
通讯作者:
Sazonova, SV
Sazonova, SV
中科院分区:
医学4区
文献类型:
--
作者:
Karpov, RS;Popov, SV;Sazonova, SV

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一项随机对照研究包括44例急性心肌梗死患者。结果发现,骨髓单核细胞的冠状动脉内注射是安全的,确保了注射的细胞在心肌中的固定,降低了IL-1 β和TNF-α的血液水平,增加了胰岛素样生长因子的含量,并且不会引起恶性心律失常。
A randomized controlled study included 44 patients with acute myocardial infarction. It was found that intracoronary injection of bone marrow mononuclear cells is safe, ensures fixation of the injected cells in the myocardium, reduces blood levels of IL-1 beta and TNF-alpha, increases the content insulin-like growth factor, and does not provoke malignant arrhythmias.