Studies on iontophoresis I Experimental studies on the causes and prevention of iontophoretic burns
Studies on iontophoresis I Experimental studies on the causes and prevention of iontophoretic burns
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DOI：
10.1097/00000441-193912000-00005
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发表时间：
1939-12-01
影响因子：
3.1
通讯作者：
Fernandez, L
中科院分区：
文献类型：
--
作者：
Molitor, H;Fernandez, L
电灼伤可能是由组织内的电解性变化引起的，而不是由电极和身体之间产生的热量或火花引起的。这些电解变化是由于电极区域(接触电极金属的主体、衬垫厚度不足或存在皮肤缺陷)过大或导电性不均匀导致的极端电流密度造成的。在电极中形成的焦散累积不足以产生灼伤，正如所应用的盐酸或NaOH浓度是电极衬垫中浓度的100倍所显示的那样；在离子导入过程中，阳极和阴极下的组织分别向酸性和碱性方向移动。人体不同部位对电流刺激的敏感性几乎是一致的。产生疼痛所需的电流与灼伤所需的电流之比约为。3：4.电极尺寸不同，安全电流密度也不同。
Galvanic burns are probably caused by electrolytic changes within the tissues and not by the generation of heat or sparking between the electrode and the body. These electrolytic changes result from extreme current densities due to excessive milliamperage or uneven conductivity over the electrode area (electrode metal touching body, insufficient thickness of padding, or existing skin defects). The accumulation of caustics formed in the electrode is insufficient to produce burns, as shown by the application of hydrochloric acid or NaOH 100 times as concentrated as found in the electrode padding; the pH of the subcut. tissues under the anode or cathode shifts during iontophoresis toward the acid and alkaline side respectively. The sensitivity of various parts of the human body to galvanic stimulation is practically uniform. The ratio between the galvanic currents required to produce pain and burns was approx. 3:4. The safe current density varies with the size of electrodes.