Spontaneous Eyeblink Activity
Spontaneous Eyeblink Activity
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DOI：
10.1016/s1542-0124(11)70007-6
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发表时间：
2011-01-01
期刊：
影响因子：
6.4
通讯作者：
Cechetti, Sheila P.
中科院分区：
文献类型：
--
作者：
Cruz, Antonio A. V.;Garcia, Denny M.;Cechetti, Sheila P.
自发性眨眼对于维持健康的眼表和清晰的视觉是必不可少的。自发眨眼率（SBR）被认为反映了由眼表介导的外周影响和中枢多巴胺能活性之间的复杂相互作用。因此，SBR是非常可变的，并取决于各种心理和医疗条件。许多不同的方法已经被用来测量SBR和上眼睑运动学在眨眼运动。每种方法都有其优缺点，具体方法的选择应根据调查的具体需要而定。虽然导致眨眼的肌肉活动的顺序已经被充分描述，但关于自发眨眼活动的神经控制的知识并不完整。泪膜在眨眼之间动态地改变，并且眨眼率的异常对眼表具有明显的影响。
Spontaneous blinking is essential for maintaining a healthy ocular surface and clarity of vision. The spontaneous blink rate (SBR) is believed to reflect a complex interaction between peripheral influences mediated by the eye surface and the central dopaminergic activity. The SBR is thus extremely variable and dependent on a variety of psychological and medical conditions. Many different methods have been employed to measure the SBR and the upper eyelid kinematics during a blink movement. Each has its own merits and drawbacks, and the choice of a specific method should be tailored to the specific needs of the investigation. Although the sequence of muscle events that leads to a blink has been fully described, knowledge about the neural control of spontaneous blinking activity is not complete. The tear film is dynamically modified between blinks, and abnormalities of the blink rate have an obvious influence on the ocular surface.