Fourier transform infrared spectroscopy as a tool to study the setting reaction in glass-ionomer cements
Fourier transform infrared spectroscopy as a tool to study the setting reaction in glass-ionomer cements
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DOI：
10.1016/j.matlet.2016.08.131
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发表时间：
2016-12
影响因子：
3
通讯作者：
Esther Valliant;B. Dickey;R. Price;D. Boyd;M. Filiaggi
中科院分区：
文献类型：
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作者：
Esther Valliant;B. Dickey;R. Price;D. Boyd;M. Filiaggi
玻璃离聚物粘固剂（GIC）已经成功地用于牙科应用数十年，并且新的粘固剂组合物不断被开发以将GIC的效用扩展到更广泛的应用中，包括整形外科。为了评价GIC的临床处理，目前使用两种主要的凝固反应指标：工作时间和凝固时间。衰减全反射傅里叶变换红外光谱（ATR-FTIR）有潜力作为实时表征这些反应的强大新工具，提供有关化学结构演变的信息，同时提高灵敏度并减少人类变异性。使用ATR-FTIR来检查将0-50重量%的聚磷酸钙添加到两种GIC中的效果：硅酸锌水泥和锗硅酸锌水泥。如使用初步的基于机械的可注射性测试方案所证明的，将CPP添加到硅酸锗锌骨水泥中的初始凝固反应的减缓对应于可注射性窗口的大幅增加，为临床应用开辟了新的可能性。我们建议，ATR-FTIR是一个有价值的工具，用于评估玻璃离子水门汀的固化反应，以补充现有的测量工作和固化时间。
Glass ionomer cements (GICs) have been successfully used in dental applications for many decades, and new cement compositions are continuously being developed to expand the utility of GICs into broader applications including orthopaedics. To evaluate the clinical handling of GICs, two main measures of the setting reaction are currently used: working time and setting time. Attenuated total reflectance fourier transform infrared spectroscopy (ATR-FTIR) has potential as a powerful new tool for real-time characterization of these setting reactions, providing information on evolving chemical structure while allowing for greater sensitivity and reduced human variability. ATR-FTIR was used to examine the effect of calcium polyphosphate addition at 0–50 wt% to two GICs: a zinc-silicate cement and a germanium zinc-silicate cement. The slowing of the initial setting reaction with CPP addition to the germanium zinc silicate cements corresponded to a large increase in the injectability window, as demonstrated using a preliminary mechanically-based injectability test protocol, opening new possibilities for clinical applications. We propose that ATR-FTIR is a valuable tool for evaluating the setting reaction of glass ionomer cements to supplement existing measurements of working and setting time.