Rhodium Catalyzed, Carbon-Hydrogen Bond Directed Hydrodefluorination of Fluoroarenes
Rhodium Catalyzed, Carbon-Hydrogen Bond Directed Hydrodefluorination of Fluoroarenes
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DOI：
10.1021/om501113j
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发表时间：
2014-12-22
期刊：
影响因子：
2.8
通讯作者：
Crimmin, Mark R.
中科院分区：
文献类型：
--
作者：
Ekkert, Olga;Strudley, Sebastian D. A.;Crimmin, Mark R.
[Cp*RhCl(Mu-Cl)](2)是一种以烃类可溶二氢铝为末端还原剂的全氟芳烃加氢脱氟预催化剂。反应直接裂解与现有C-H键相邻的C-F键，区域选择性高(98.5-99%)。一个含有稀有Al-H-Rh官能团的异双金属络合物已被分离出来，并显示出催化活性。
[Cp*RhCl(mu-Cl)](2) is reported as a highly efficient and selective precatalyst for the hydrodefluorination of perfluoroarenes using a hydrocarbon-soluble aluminum dihydride as the terminal reductant. Reactions are directed to cleave a C-F bond adjacent to an existing C-H bond with high regioselectivity (98.5-99%). A heterobimetallic complex containing an extremely rare Al-H-Rh functional group has been isolated and shown to be catalytically competent.